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Snakebite is a global public health concern, which often occurs in tropical and subtropical underdeveloped areas, but it is often neglected. In the southern China, Naja naja atra (Chinese cobra) is a common venomous snake that causes swelling and necrosis of local tissues, even amputation and death. Currently, the main therapy is the administration of Naja atra antivenom, which greatly reduces mortality. However, the antivenom is not particularly effective in the improvement of local tissue necrosis. Clinically, antivenom is mainly administered intravenously. We speculated that the method of injection influences the efficacy of antivenom. In this study, the rabbit model was used to explore the effects of different antivenom injection methods on systemic and local poisoning symptoms. If topical injection of antivenom contributes to ameliorate tissue necrosis, then we need to reconsider the use of Naja atra antivenom. [ABSTRACT FROM AUTHOR]

What is known and objective: Anti‐CD19 CAR‐T cell therapy is effective in B‐cell lymphoma. However, it is rarely used in lymphoma combined with other malignant tumours. Case description: A relapsed/refractory follicular lymphoma (r/r FL) patient underwent anti‐CD19 CAR‐T cell therapy and achieved complete response to lymphoma. However, gastric adenocarcinoma (GAC) was diagnosed during the cellular therapy. After infusion of CAR‐T cells, he received curative treatment for GAC, and maitained complete response in both r/r FL and GAC after the treatment. What is new and conclusion: Anti‐CD19 CAR‐T therapy is an effective treatment for r/r FL, also provided opportunity for the sequential therapy of GAC, and remained significant quality of life afterwards. [ABSTRACT FROM AUTHOR]

This article makes relevant research and analysis from theory and practice, respectively. At the same time, with reference to the current state of the Internet, relative analysis was used to focus on the state of commercial banks. The analysis mainly focuses on the problems encountered in the current Internet development in various forms such as the bank's sales status and customer products. In addition, it really made a reasonable opinion about the relevant sales status of this bank. It systematically studied the development history of marketing products of financial blockchain in China's financial blockchain and analyzed the process of gradual improvement of the functions and characteristics of marketing products of financial blockchain in China. The characteristics and shortcomings of the marketing products of the financial blockchain were discussed in detail, and from the perspective of technological innovation, the application of emerging technologies in the marketing of China's financial blockchain was analyzed. This article analyzes the many challenges and opportunities faced by security firms in the development of the Internet. Under the new situation, what kind of development model to adopt and how to transform and upgrade is the strategic proposition that security firms must think about. Based on Internet finance, this article finds that the equity crowdfunding model can be selected in the future development of security companies. On the one hand, the use of equity crowdfunding by security firms can enhance their direct financing capabilities, which will benefit the security industry, especially Internet security firms. On the other hand, through equity crowdfunding, security companies can expand direct financing channels for small, medium, and micro enterprises to promote entrepreneurship. The paper promotes the development of Internet finance, thereby improving the ability of the capital market to serve the real economy. [ABSTRACT FROM AUTHOR]