1. Insomnia in Adults With Chronic Hepatitis B, Liver Failure, and Cirrhosis: A Case-Control Study.
- Author
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Guo, Hui‐Min, Liu, Mei, Xiang, Yu‐Tao, Zhao, Jing, Ungvari, Gabor S., Correll, Christoph U., Ng, Chee H., Chiu, Helen F.K., and Duan, Zhong‐Ping
- Subjects
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CHI-squared test , *CONFIDENCE intervals , *INSOMNIA , *CIRRHOSIS of the liver , *LIVER failure , *PAIRED comparisons (Mathematics) , *RESEARCH funding , *RURAL population , *SCALE analysis (Psychology) , *STATISTICAL hypothesis testing , *CROSS-sectional method , *CASE-control method , *DATA analysis software , *DESCRIPTIVE statistics , *CHRONIC hepatitis B , *ODDS ratio , *MANN Whitney U Test , *ADULTS - Abstract
Purpose: To determine the frequency and socio‐demographic/clinical correlates of insomnia in patients with chronic hepatitis B, hepatitis B virus (HBV)‐related liver failure, and cirrhosis. Design and Methods: Up to 120 patients with HBV‐related diseases and 40 matched healthy controls were recruited. Depressive and anxiety symptoms, early, middle, and late insomnia were measured. Findings: The frequency of ≥1 type of insomnia was 64.2% in patients and 35.0% in controls; frequencies of early, middle, and late insomnia in patients were 39.2%, 42.5%, and 48.3%, respectively, compared to 22.5%, 10.0%, and 25.0% in controls. Urban residency was independently associated with less insomnia of any type, accounting for 22.6% of the variance. Practice Implications: A considerable proportion of patients with HBV‐related diseases suffer from insomnia that warrants more attention in clinical practice. [ABSTRACT FROM AUTHOR]
- Published
- 2017
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