Search

Medical image information may be polluted by noise in the process of generation and transmission, which will seriously hinder the follow-up image processing and medical diagnosis. In medical images, there is a typical mixed noise composed of additive white Gaussian noise (AWGN) and impulse noise. In the conventional denoising methods, impulse noise is first removed, followed by the elimination of white Gaussian noise (WGN). However, it is difficult to separate the two kinds of noises completely in practical application. The existing denoising algorithm of weight coding based on sparse nonlocal regularization, which can simultaneously remove AWGN and impulse noise, is plagued by the problems of incomplete noise removal and serious loss of details. The denoising algorithm based on sparse representation and low rank constraint can preserve image details better. Thus, a medical image denoising algorithm based on sparse nonlocal regularization weighted coding and low rank constraint is proposed. The denoising effect of the proposed method and the original algorithm on computed tomography (CT) image and magnetic resonance (MR) image are compared. It is revealed that, under different σ and ρ values, the PSNR and FSIM values of CT and MRI images are evidently superior to those of traditional algorithms, suggesting that the algorithm proposed in this work has better denoising effects on medical images than traditional denoising algorithms.

The impulse noise in CT image was removed based on edge-preserving median filter algorithm. The sparse nonlocal regularization algorithm weighted coding was used to remove the impulse noise and Gaussian noise in the mixed noise, and the peak signal-to-noise ratio (PSNR) and structural similarity index (SSIM) were calculated to evaluate the quality of the denoised CT image. It was found that in nine different proportions of Gaussian noise and salt-and-pepper noise in Shepp-Logan image and CT image processing, the PSNR and SSIM values of the proposed denoising algorithm based on edge-preserving median filter (EP median filter) and weighted encoding with sparse nonlocal regularization (WESNR) were significantly higher than those of using EP median filter and WESNR alone. It was shown that the weighted coding algorithm based on edge-preserving median filtering and sparse nonlocal regularization had potential application value in low-dose CT image denoising.