1. Resveratrol Oligomers for the Prevention and Treatment of Cancers
- Author
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You-Qiu Xue, Jin-Ming Di, Xing Wei, Yun Luo, Ke-Jun Cheng, and Zhi Shi
- Subjects
Aging ,endocrine system diseases ,Polymers ,Apoptosis ,Review Article ,Resveratrol ,Biochemistry ,chemistry.chemical_compound ,Human health ,Neoplasms ,Stilbenes ,Humans ,lcsh:QH573-671 ,skin and connective tissue diseases ,chemistry.chemical_classification ,lcsh:Cytology ,Phytoalexin ,organic chemicals ,food and beverages ,Cell Cycle Checkpoints ,Cell Biology ,General Medicine ,Antineoplastic Agents, Phytogenic ,chemistry ,hormones, hormone substitutes, and hormone antagonists - Abstract
Resveratrol (3,4′,5-trihydroxystilbene) is a naturally derived phytoalexin stilbene isolated from grapes and other plants, playing an important role in human health and is well known for its extensive bioactivities, such as antioxidation, anti-inflammatory, anticancer. In addition to resveratrol, scientists also pay attention to resveratrol oligomers, derivatives of resveratrol, which are characterized by the polymerization of two to eight, or even more resveratrol units, and are the largest group of oligomeric stilbenes. Resveratrol oligomers have multiple beneficial properties, of which some are superior in activity, stability, and selectivity compared with resveratrol. The complicated structures and diverse biological activities are of significant interest for drug research and development and may provide promising prospects as cancer preventive and therapeutical agents. This review presents an overview on preventive or anticancer properties of resveratrol oligomers.
- Published
- 2014