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3. Correlation between Density and Resorption of Fresh-Frozen and Autogenous Bone Grafts

Author

G. Ghiacci, Guido Maria Macaluso, Simone Lumetti, Claudio Marchetti, Ugo Consolo, Carlo Galli, Andrea Toffoli, Mauro Bonanini, Attilio Carlo Salgarelli, Edoardo Manfredi, Lumetti S, Galli C, Manfredi E, Consolo U, Marchetti C, Ghiacci G, Toffoli A, Bonanini M, Salgarelli A, and Macaluso GM.

Subjects
Adult, Male, medicine.medical_specialty, Article Subject, Bone density, lcsh:Medicine, Transplantation, Autologous, General Biochemistry, Genetics and Molecular Biology, Bone resorption, Young Adult, Bone Density, Alveolar Process, medicine, Frozen Sections, Humans, In patient, Bone Resorption, Autogenous bone, density and resorption, Frozen section procedure, Bone Transplantation, General Immunology and Microbiology, business.industry, Alveolar process, lcsh:R, General Medicine, Middle Aged, fresh-frozen bone grafts, AUTOGENOUS BONE, Resorption, Surgery, medicine.anatomical_structure, Clinical Study, Fresh frozen, Female, business
Abstract

Trial Design. This analysis compared the outcome of fresh-frozen versus autologous bone block grafts for horizontal ridge augmentation in patients with Cawood and Howell class IV atrophies.Methods. Seventeen patients received autologous grafts and 21 patients received fresh-frozen bone grafts. Patients underwent CT scans 1 week and 6 months after surgery for graft volume and density analysis.Results. Two autologous and 3 fresh-frozen grafts failed. Autologous and fresh-frozen grafts lost, respectively, 28% and 46% of their initial volume(P=0.028). It is noteworthy that less dense fresh-frozen blocks lost more volume than denser grafts (61% versus 16%).Conclusions. According to these 6-month results, only denser fresh-frozen bone graft may be an acceptable alternative to autologous bone for horizontal ridge augmentation. Further studies are needed to investigate its behaviour at longer time points.

Published
2014
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