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Start Over Author "Michelangelo Iannone" Publisher hindawi limited
2 results on '"Michelangelo Iannone"'

1. MicroRNAs as Biomarkers in Thyroid Carcinoma

Author

Marilena Celano, Francesca Rosignolo, Valentina Maggisano, Valeria Pecce, Michelangelo Iannone, Diego Russo, and Stefania Bulotta

Subjects
Genetics, QH426-470
Abstract

Optimal management of patients with thyroid cancer requires the use of sensitive and specific biomarkers. For early diagnosis and effective follow-up, the currently available cytological and serum biomarkers, thyroglobulin and calcitonin, present severe limitations. Research on microRNA expression in thyroid tumors is providing new insights for the development of novel biomarkers that can be used to diagnose thyroid cancer and optimize its management. In this review, we will examine some of the methods commonly used to detect and quantify microRNA in biospecimens from patients with thyroid tumor, as well as the potential applications of these techniques for developing microRNA-based biomarkers for the diagnosis and prognostic evaluation of thyroid cancers.

Published
2017
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2. MicroRNAs as Biomarkers in Thyroid Carcinoma

Author

Stefania Bulotta, Michelangelo Iannone, Marilena Celano, Valeria Pecce, Diego Russo, Francesca Rosignolo, and Valentina Maggisano

Subjects
0301 basic medicine, Oncology, endocrine system, medicine.medical_specialty, lcsh:QH426-470, endocrine system diseases, thyroid cancer, microRNA, biomarkers, medicine.medical_treatment, Pharmaceutical Science, Review Article, Biochemistry, thyroid, Thyroid carcinoma, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, microRNA, Genetics, medicine, micrornas, Molecular Biology, Thyroid tumors, Thyroid cancer, business.industry, Thyroid, medicine.disease, Optimal management, lcsh:Genetics, 030104 developmental biology, medicine.anatomical_structure, Calcitonin, 030220 oncology & carcinogenesis, Immunology, Thyroglobulin, pharmacology, business
Abstract

Optimal management of patients with thyroid cancer requires the use of sensitive and specific biomarkers. For early diagnosis and effective follow-up, the currently available cytological and serum biomarkers, thyroglobulin and calcitonin, present severe limitations. Research on microRNA expression in thyroid tumors is providing new insights for the development of novel biomarkers that can be used to diagnose thyroid cancer and optimize its management. In this review, we will examine some of the methods commonly used to detect and quantify microRNA in biospecimens from patients with thyroid tumor, as well as the potential applications of these techniques for developing microRNA-based biomarkers for the diagnosis and prognostic evaluation of thyroid cancers.

Published
2017

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