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At present, there are some key issues in the traditional preimmersion method for reducing the collapsibility of the loess ground, such as the difficulty in determining the total water consumption and the long immersion time. In response to these issues, a new method, the borehole preimmersion method, is presented, and a specific theoretical design model is proposed for application in projects. The method is specifically discussed from a new perspective, and the diffusion mechanism and evolution law of water in the ground are presented in detail through theoretical analysis and numerical calculation, respectively. The water diffusion is a mushroom-type form for a single water injection hole immersed in water. A calculation model derived for a single water injection hole or a group of water injection holes based on the research results is used to calculate the volumes of soaked loess and the total water consumption. Through an in situ immersion test, the treatment effect of this method is evaluated to verify the rationality of the method and the theoretical calculation model proposed in this study, which provides a new method and theoretical framework for effectively reducing the collapsibility of the loess ground.

In the geogenetic overburden excavation of underground space projects (such as comprehensive pipe corridors or subways), the foundation stress is in an unloading state. The effect(s) from the unloading on the coefficient of subsidence in the loess area should be considered. In this study, to explore the effect of unloading on the collapsibility of loess, the collapsible loess in the Guanzhong area was considered as the research object. An expression for the unloading collapse coefficient was established based on the unloading stress ratio, unloading collapse ratio, and other parameters. The influence of the unloading on the loess collapse coefficient was studied using an indoor collapsibility test, and the function form and parameters for the expression were determined. As combined with the field test, the accuracy of the expression for the unloading coefficient was verified based on the test value for the specific collapsibility, calculated value for the specific collapsibility, and calculated value for the unloading collapsibility.

The knee joint, as the main lower limb motor joint, is the most vulnerable and susceptible joint. The knee injuries considerably impact the normal living ability and mental health of patients. Understanding the biomechanics of a normal and diseased knee joint is in urgent need for designing knee assistive devices and optimizing a rehabilitation exercise program. In this paper, we systematically searched electronic databases (from 2000 to November 2019) including ScienceDirect, Web of Science, PubMed, Google Scholar, and IEEE/IET Electronic Library for potentially relevant articles. After duplicates were removed and inclusion criteria applied to the titles, abstracts, and full text, 138 articles remained for review. The selected articles were divided into two groups to be analyzed. Firstly, the real movement of a normal knee joint and the normal knee biomechanics of four kinds of daily motions in the sagittal and coronal planes, which include normal walking, running, stair climbing, and sit-to-stand, were discussed and analyzed. Secondly, an overview of the current knowledge on the movement biomechanical effects of common knee musculoskeletal disorders and knee neurological disorders were provided. Finally, a discussion of the existing problems in the current studies and some recommendation for future research were presented. In general, this review reveals that there is no clear assessment about the biomechanics of normal and diseased knee joints at the current state of the art. The biomechanics properties could be significantly affected by knee musculoskeletal or neurological disorders. Deeper understanding of the biomechanics of the normal and diseased knee joint will still be an urgent need in the future.

Diabetic retinopathy is one of the main causes of blindness in human eyes, and lesion segmentation is an important basic work for the diagnosis of diabetic retinopathy. Due to the small lesion areas scattered in fundus images, it is laborious to segment the lesion of diabetic retinopathy effectively with the existing U-Net model. In this paper, we proposed a new lesion segmentation model named FFU-Net (Feature Fusion U-Net) that enhances U-Net from the following points. Firstly, the pooling layer in the network is replaced with a convolutional layer to reduce spatial loss of the fundus image. Then, we integrate multiscale feature fusion (MSFF) block into the encoders which helps the network to learn multiscale features efficiently and enrich the information carried with skip connection and lower-resolution decoder by fusing contextual channel attention (CCA) models. Finally, in order to solve the problems of data imbalance and misclassification, we present a Balanced Focal Loss function. In the experiments on benchmark dataset IDRID, we make an ablation study to verify the effectiveness of each component and compare FFU-Net against several state-of-the-art models. In comparison with baseline U-Net, FFU-Net improves the segmentation performance by 11.97%, 10.68%, and 5.79% on metrics SEN, IOU, and DICE, respectively. The quantitative and qualitative results demonstrate the superiority of our FFU-Net in the task of lesion segmentation of diabetic retinopathy. [ABSTRACT FROM AUTHOR]