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Your search keyword '"Rojas‐Villarraga, Adriana"' showing total 15 results
Start Over Author "Rojas‐Villarraga, Adriana" Publisher hindawi limited
15 results on '"Rojas‐Villarraga, Adriana"'

7. Autoimmune Thyroid Disease in Rheumatoid Arthritis: A Global Perspective

Author

Cárdenas Roldán, Jorge, primary, Amaya-Amaya, Jenny, additional, Castellanos-de la Hoz, Juan, additional, Giraldo-Villamil, Juliana, additional, Montoya-Ortiz, Gladys, additional, Cruz-Tapias, Paola, additional, Rojas-Villarraga, Adriana, additional, Mantilla, Rubén D., additional, and Anaya, Juan-Manuel, additional

Published
2012
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9. Usefulness of Patients-Reported Outcomes in Rheumatoid Arthritis Focus Group

Author

Amaya-Amaya, Jenny, primary, Botello-Corzo, Diana, additional, Calixto, Omar-Javier, additional, Calderón-Rojas, Rolando, additional, Domínguez, Aura-Maria, additional, Cruz-Tapias, Paola, additional, Montoya-Ortiz, Gladis, additional, Mantilla, Ruben-Dario, additional, Anaya, Juan-Manuel, additional, and Rojas-Villarraga, Adriana, additional

Published
2012
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14. GDF15(MIC1) H6D Polymorphism Does Not Influence Cardiovascular Disease in a Latin American Population with Rheumatoid Arthritis.

Author

Amaya-Amaya, Jenny, Rojas-Villarraga, Adriana, Molano-Gonzalez, Nicolas, Montoya-Sánchez, Laura, Nath, Swapan K., and Anaya, Juan-Manuel

Subjects
*GENETIC polymorphisms, *CARDIOVASCULAR diseases, *RHEUMATOID arthritis, *AUTOIMMUNE diseases, *IMMUNE response
Abstract

Objective. Rheumatoid arthritis (RA) is the most common autoimmune arthropathy worldwide. The increased prevalence of cardiovascular disease (CVD) in RA is not fully explained by classic risk factors. The aim of this study was to determine the influence of rs1058587 SNP within GDF15(MIC1) gene on the risk of CVD in a Colombian RA population. Methods. This was a cross-sectional analytical study in which 310 consecutive Colombian patients with RA and 228 age- and sex-matched controls were included and assessed for variables associated with CVD. The mixed cluster methodology based on multivariate descriptive methods such as principal components analysis and multiple correspondence analyses and regression tree (CART) predictive model were performed. Results. Of the 310 patients, 87.4% were women and CVD was reported in 69.5%. Significant differences concerning GDF15 polymorphism were not observed between patients and controls. Mean arterial pressure, current smoking, and some clusters were significantly associated with CVD. Conclusion. GDF15 (rs1058587) does not influence the development of CVD in the population studied. [ABSTRACT FROM AUTHOR]

Published
2015
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15. Autoimmune Thyroid Disease in Rheumatoid Arthritis: A Global Perspective.

Author

Roldán, Jorge Cárdenas, Amaya-Amaya, Jenny, Castellanos-de la Hoz, Juan, Giraldo-Villamil, Juliana, Montoya-Ortiz, Gladys, Cruz-Tapias, Paola, Rojas-Villarraga, Adriana, Mantilla, Rubén D., and Anaya, Juan-Manuel

Abstract

Objective. To determine the prevalence and impact of autoimmune thyroid disease (AITD) in patients with rheumatoid arthritis (RA). Methods. Eight-hundred patients were included. The association between AITD and RA was analyzed was analyzed by bivariate and multivariate analysis. In addition, a literature review was done focusing on geographical variations. Results. In our cohort the prevalence of AITD was 9.8% while the presence of antibodies was 37.8% for antithyroperoxidase enzyme (TPOAb) and 20.8% for antithyroglobulin protein (TgAb). The presence of type 2 diabetes, thrombosis, abnormal body mass index, and a high educational level was positively associated with AITD. The literature review disclosed a geographical variation of AITD in RA ranging from 0.5% to 27%. Autoantibody prevalence ranges from6%to 31% for TgAb, 5% to 37% for TPOAb, and from 11.4% to 32% for the presence of either of the two. Conclusion. AITD is not uncommon in RA and should be systematically assessed since it is a risk factor for developing diabetes and cardiovascular disease. These results may help to further study the commonmechanisms of autoimmune diseases, to improve patients' outcome, and to define public health policies. An international consensus to accurately diagnose AITD is warranted. [ABSTRACT FROM AUTHOR]

Published
2012
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