1. Recent Advances in the Total Synthesis of Tetramic Acid-Containing Natural Products
- Author
-
Wen-Ju Bai, Chen Lu, and Xiqing Wang
- Subjects
Natural product ,010405 organic chemistry ,Chemistry ,Total synthesis ,Nanotechnology ,General Chemistry ,Tetramic acid ,010402 general chemistry ,01 natural sciences ,Natural (archaeology) ,0104 chemical sciences ,lcsh:Chemistry ,chemistry.chemical_compound ,lcsh:QD1-999 ,Biochemical engineering - Abstract
With incredible bioactivities and fascinating structural complexities, tetramic acid- (TA-) containing natural products have attracted favorable attention among the organic chemistry community. Although the construction of the TA core is usually straightforward, the intricate C3-side chain sometimes asks for some deliberative strategy so as to fulfill an elegant total synthesis. This review mainly covers some exceptional synthetic examples for each type of natural product in recent years, showcasing the great achievements as well as unsettled obstacles in this area, in the hope of accelerating the synthetic and biological investigations for this unique type of natural product.
- Published
- 2016