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Using an incentive measure to encourage people to share their private parking spaces could be an effective strategy for urban parking problems. This paper discusses an innovative mechanism of shared parking, 'FlexPass,' which applies a reverse auction in which drivers propose bids in line with their individual expectations to share their idle parking spaces. The auction mechanism, hypotheses on bidding process principles, the competitive environment, and the risk-averse decisions of providers with regard to parking spaces are analysed to explore the sustainability of the economic benefits obtained for FlexPass parking spaces. A total of 216 respondents from the University of California, Berkeley, were invited to participate in bidding in an actual survey during their daily use of parking spaces. The analytical results show that operational rules based on risk aversion can enable profit-seeking with a bounded capability to obtain considerable economic benefits and release parking resources in an environment of demand competition. Particularly in some scenarios, FlexPass would sacrifice a certain monetary income to ensure the perceived benefits of parking space providers. With the improvement of people's enthusiasm for participating in shared parking, the benefits to individuals and parking lots would be further enhanced, suggesting that our mechanism can operate sustainably over the long term. These findings are helpful for policymakers to formulate feasible shared parking policies from the perspective of monetary incentives., Author(s): Liangpeng Gao [1,2]; Yue Zheng (corresponding author) [2,3]; Wenliang Jian [1,4]; Yanjie Ji [2]; Dounan Tang [5] 1. Introduction As an important part of urban transport systems, static traffic, [...]

Flexible transit services, which bring together the characteristics of fixed-route transit and demand-responsive transit, have been proven to be cost-efficient in low-density residential areas. In this paper, a methodology is proposed to assist planners in making better decisions when choosing between route deviation policy and point deviation policy, which are two promising types of flexible transit services. A user cost function is developed to measure the service quality of the transit systems, and analytical models are constructed to compare the system performance under both expected and unexpected demand levels. Based on the experiments for various scenarios over a real-life transit example, the critical demands, which represent the switching point between the two competing service policies, have been derived. Our findings show that point deviation policy is more efficient at low-demand levels, while route deviation policy is a better choice at low-to-moderate demand levels. At unexpectedly high demand levels, route deviation policy is better able to accommodate rejected passengers than point deviation policy., 1. Introduction With the acceleration of urbanization in recent decades, an increasing number of suburban areas with low population density have arisen. The increasing dispersion of population results in a [...]

Curcumin is a natural phenolic compound extracted from the herb Curcuma longa L. rhizome and has received much attention on account of its biological properties. However, its poor solubility and low bioavailability limit its use. The purpose of this study was to synthesize curcumin-loaded nanoliposomes (Cur-NLs) to improve their bioavailability and evaluate the hepatoprotective effect of Cur-NLs against tetrachloromethane- (CCl4-) induced acute liver injury in mice. We prepared Cur-NLs by thin film dispersion method, and the characterizations of Cur-NLs were measured by transmission microscope, laser particle size analyzer, infrared spectrometer, and X-ray diffraction. After 14 days pretreatment of Cur-NLs, free curcumin, silybin, or PBS, the models of acute liver injury were established by CCl4 intraperitoneal injection in mice. The organ index, biochemical liver function parameters, histopathology, and antioxidant enzyme activities of liver tissues were measured further to evaluate the protective effects of Cur-NLs on liver injury. Compared with the CCl4 model control group, pretreatment of Cur-NLs effectively reduced the serum levels of ALT, AST, and ALP and attenuated the hepatic necrosis induced by CCl4 intoxication. Furthermore, Cur-NL pretreatment remarkably exhibited decreased MDA level and increased SOD, GPx, and CAT activities compared to CCl4 model control group. Compared with the free curcumin group, the Cur-NLs also showed a better hepatoprotective effect. These observations imply that Cur-NLs act as a promising hepatoprotective agent in reducing liver oxidative stress produced by different stress factors. [ABSTRACT FROM AUTHOR]