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A system for observing bladder cancer cells in form of a miniaturized fluorescence microscope has been developed. Attention has turned to integrate this system in an existing LTCC (Low Temperature Cofired Ceramics) module. Software with a region detecting algorithm has been written to automatically detect the captured images. The cancer specimen was marked with hypericin, which is selective on bladder cancer cells. After coloring the specimen was excited with green light of a high power LED. The red emitting hypericin marked cells were captured by a CMOS chip and evaluated with the software to confirm or negate a suspicion of cancer.

Based on flow models applied in former analyses, three dimensional numerical flow simulations were performed for a spherical reactor cell of a biological monitoring module with respect to different inflow configurations and respective mass flow rates. Time - dependent simulations were performed for the case of dyed water and clear water flowing through different inlets at varying mass flow rates into the spherical cavity of reactor cell and channel system which connects the relevant measuring ports of the monitoring module. Spectroscopic analyses of light absorption at a port have been carried out and the results compared with the local concentration distribution predicted for this port by means of FE - analyses (Finite Element) using the CFD (Computational Fluid Dynamics) - program package of Fluent Inc.

In order to study the mixing of two liquids in a reaction chamber finite element analyses have been conducted. Different operating conditions like the filling of the empty reaction cell with liquids, mixing of fluids with different doping concentrations have been analyzed in dependence on varying flow velocities of liquids. To verify the results of simulation a reaction cell has been built up using LTCC-technology (low temperature cofired ceramic). Top and bottom side of the reaction cell were covered with a glass plate which enables the optical inspection and analyses of the sequence of mixing of coloured liquids.