1. A Novel Handheld Diffuse Optical Spectroscopy System Implementation Based on High-Accuracy Multidimensional Imaging Reconstruction Model for Human Breast Healthcare Applications
- Author
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Jia-Jiun Guo, Wen-Jun Wu, and Wai-Chi Fang
- Subjects
Digital signal processor ,Computer science ,business.industry ,Physics::Medical Physics ,0206 medical engineering ,Detector ,ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION ,Reconstruction algorithm ,02 engineering and technology ,Inverse problem ,020601 biomedical engineering ,Diffuse optical imaging ,020210 optoelectronics & photonics ,Control theory ,0202 electrical engineering, electronic engineering, information engineering ,Wireless ,business ,Image resolution ,Computer hardware - Abstract
Diffuse Optical Tomography (DOT) is a relatively novel, nonionizing and noninvasive technique for breast tumor imaging. Due to the diffusive nature of light propagation, the inverse problem is highly ill-posed. In this study, we propose the modified Beer-Lambert’s law that reduces the number of unknown values to reduce the ill-posedness issue. An integrated mobile DOT system is proposed. The system comprises a front-end circuit and an integrated digital signal processor. The sources and the detectors are distributed hexagonal geometry for increasing the spatial resolution. The processor included the front-end controller, the iteration algorithm engine and wireless communication controller were implemented on FPGA. The functionalities of the proposed system were validated using a breast phantom. Extensive experimental results illustrated to show the performance of the proposed system. The depth of the tumor detected by the system is 20mm.
- Published
- 2019
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