This chapter is a review of published research papers, books, book chapters, unpublished scientific reports prepared by research organisations, and expert talk about heavy metal pollution. This chapter also summarises the research studies conducted in Coimbatore and a summary of the studies says that very tiny information is available on heavy metals in soil, water, and air components. Till now heavy metals in plants, plant products, animals, animal products, bioaccumulation in humans, and its impacts are not accounted in this region. Further, these chapters identify the research gaps, and research interventions are required to assess the heavy metals contaminations in different ecosystems. It also highlights the need for long-term monitoring of heavy metals in the ground, surface water, food materials, agricultural products produced in the contaminated regions. The chapter concludes with a need for study on human health impacts, restoration, and remediation measures required in Coimbatore regions.