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20 results on '"Casagrande, C."'

1. Alkaloids of Ocotea brachybotra.

Author

Vecchietti V, Casagrande C, and Ferrari G

Subjects
Aporphines isolation & purification, Magnetic Resonance Spectroscopy, Morphinans isolation & purification, Alkaloids isolation & purification, Plants, Medicinal analysis
Abstract

Aporphine, proaporphine and morphinane alkaloids were isolated from the leaves of a Brazilian Lauracea, Ocotea brachybotra (Meiss.) Mez. The known alkaloids were identified through their physico-chemical properties as: (I) (+/-)-glaziovine, (II) dicentrine, (III) ocopodine, (IV) cassynthicine, (V) predicentrine, (VI) leucoxine, (IX) sinacutine and (X) pallidine. The structure of (VI) leucoxine was confirmed by a detailed analysis of the N.M.R. spectra recorded in various conditions. New morphinane alkaloids, (XI) ocobotrine and (XII) 14-espisinomenine, having the unusual B/C-trans configuration were also isolated. Their structures were determined using spectroscopic methods and chemical correlations.

Published
1977

3. New aporphine alkaloids of Ocotea minarum.

Author

Vecchietti V, Casagrande C, Ferrari G, and Severini Ricca G

Subjects
Alkaloids analysis, Brazil, Chemical Phenomena, Chemistry, Aporphines isolation & purification, Plants, Medicinal analysis
Abstract

Fourteen aporphine alkaloids were isolated from the leaves of a Brazilian Lauracea, Ocotea minarum Nees (Mez). The known alkaloids were identified through their physico-chemical properties as: leucoxylonine (VII), dicentrine (IV), ocoteine (V), leucoxine (VI), ocopodine (VIII), predicentrine (IX), dicentrinone (XIV) and thalicminine (XV). Six new aporphine alkaloids were also isolated: ocotominarine (I), ocominarine (III), nor-leucoxylonine (XI), iso-oconovine (xii), 4-hydroxydicentrine (XIII) and ocominarone (XVI). Their structures were determined using spectroscopic methods and chemical correlations.

Published
1979

4. Synthesis and antiarrhythmic activity of 5,5-disubstituted-3-aminoalkylhydantions and some heterocyclic and noncyclic analogues.

Author

Casagrande C, Galli A, Ferrini R, Miragoli G, and Ferrari G

Subjects
Alkylation, Amides chemical synthesis, Animals, Diethylamines, Dimethylamines, Disopyramide chemical synthesis, Heterocyclic Compounds chemical synthesis, Hydantoins therapeutic use, Isomerism, Mice, Piperidines chemical synthesis, Quinidine therapeutic use, Structure-Activity Relationship, Urea chemical synthesis, Ventricular Fibrillation drug therapy, Arrhythmias, Cardiac drug therapy, Hydantoins chemical synthesis
Published
1974

5. Capillary protective and antiinflammatory activity of alpha,4-dihydroxy-3-methoxyacetophenone and some of its esters.

Author

Casagrande C, Invernizzi A, Ferrini R, and Miragoli G

Subjects
Acetophenones chemical synthesis, Acetophenones therapeutic use, Acetophenones toxicity, Acetophenones urine, Animals, Edema drug therapy, Esters pharmacology, Esters toxicity, Female, Infrared Rays, Male, Mice, Rats, Skin drug effects, Spectrum Analysis, Acetophenones pharmacology, Anti-Inflammatory Agents, Capillary Permeability drug effects, Capillary Resistance drug effects
Published
1968

6. Synthesis of some isoindolines and 1,2,3,4-tetrahydroisoquinolines and their evaluation as alpha-adrenergic and adrenergic neuron blocking agents.

Author

Casagrande C, Galli A, Ferrini R, and Miragoli G

Subjects
Adrenergic alpha-Antagonists chemical synthesis, Adrenergic alpha-Antagonists pharmacology, Adrenergic beta-Antagonists chemical synthesis, Adrenergic beta-Antagonists pharmacology, Animals, Cats, Evaluation Studies as Topic, Heart drug effects, Ileum drug effects, Indoles pharmacology, Isoquinolines chemical synthesis, Mice, Nictitating Membrane drug effects, Quinolines pharmacology, Rats, Structure-Activity Relationship, Indoles chemical synthesis, Quinolines chemical synthesis, Sympatholytics chemical synthesis
Published
1972

12. Synthesis and pharmacological evaluation of respiratory stimulant amides of imidazo(1,2-a)pyridine-2,3-dicarboxylic acids.

Author

Casagrande C, Ferrini R, Miragoli G, and Ferrari G

Subjects
Animals, Blood Pressure drug effects, Carboxylic Acids chemical synthesis, Carboxylic Acids pharmacology, Carboxylic Acids toxicity, Cyclization, Dogs, Heart Rate drug effects, Imidazoles chemical synthesis, Imidazoles pharmacology, Imidazoles toxicity, Lethal Dose 50, Magnetic Resonance Spectroscopy, Mice, Rabbits, Spectrophotometry, Infrared, Stimulation, Chemical, Structure-Activity Relationship, Pyridines chemical synthesis, Pyridines pharmacology, Pyridines toxicity, Respiration drug effects
Published
1972

14. Derivatives of pyrrolo(2,1-a)isoquinoline. II. Monoamides of 5,6-dihydropyrrolo(2,1-a)isoquinoline-2,3-dicarboxylic acids.

Author

Casagrande C, Invernizzi A, Ferrini R, and Miragoli G

Subjects
Animals, Blood Pressure drug effects, Cardiovascular System drug effects, Cats, Dicarboxylic Acids pharmacology, Dicarboxylic Acids toxicity, Dogs, Female, Guinea Pigs, Heart Rate drug effects, Isoquinolines chemical synthesis, Isoquinolines pharmacology, Isoquinolines toxicity, Male, Mice, Papillary Muscles drug effects, Pulse drug effects, Pyrroles chemical synthesis, Pyrroles pharmacology, Pyrroles toxicity, Structure-Activity Relationship, Dicarboxylic Acids chemical synthesis
Published
1972

15. 3,4-0-diacyl derivatives of dopamine.

Author

Casagrande C and Ferrari G

Subjects
Acetates chemical synthesis, Benzyl Compounds chemical synthesis, Dioxins, Hydrogenation, Spectrophotometry, Infrared, Structure-Activity Relationship, Succinates, Dopamine chemical synthesis
Published
1973

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