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Start Over Descriptor "acute ischemic cerebrovascular disease" Publisher impact journals, llc
2 results on '"acute ischemic cerebrovascular disease"'

1. Association of antinuclear antibodies with the risk of intracranial arterial stenosis

Author

Lan Tan, Jin-Tai Yu, Lin Tong, Xian-Zhen Peng, Yong-An Sun, Xiao-He Hou, Qiu Han, and Xu Zheng

Subjects
Male, musculoskeletal diseases, Aging, medicine.medical_specialty, Anti-nuclear antibody, Population, antinuclear antibodies, Comorbidity, Constriction, Pathologic, intracranial arterial stenosis, Severity of Illness Index, Magnetic resonance angiography, Brain Ischemia, immune system diseases, Risk Factors, Internal medicine, acute ischemic cerebrovascular disease, Odds Ratio, medicine, Humans, Statistical analysis, In patient, skin and connective tissue diseases, education, Acute ischemic stroke, Aged, Aged, 80 and over, education.field_of_study, medicine.diagnostic_test, Arterial stenosis, business.industry, magnetic resonance angiography, Cell Biology, Middle Aged, stomatognathic diseases, Antibodies, Antinuclear, Female, Disease Susceptibility, Intracranial Arterial Diseases, business, Biomarkers, Research Paper
Abstract

The prevalence of intracranial arterial stenosis (IAS) as well as antinuclear antibody (ANA) positivity was found to be higher in Asians than that in the Western population. To investigate the relation of ANAs with IAS in patients with acute ischemic cerebrovascular disease, we enrolled 2492 patients with acute ischemic stroke or transient ischemic attack into the study. All the patients were categorized into 3 groups according to the IAS burden. Multinomial logistic regression analyses were used in statistical analysis. The positive rate of ANAs in the IAS ≥ 2 group was higher than that in the single IAS group and the no IAS group (p75 years old). In summary, ANAs are associated with IAS in patients with acute ischemic cerebrovascular disease.

Published
2020
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2. Association of antinuclear antibodies with the risk of intracranial arterial stenosis.

Author

Sun YA, Han Q, Hou XH, Peng XZ, Tong L, Zheng X, Yu JT, and Tan L

Subjects
Aged, Aged, 80 and over, Biomarkers, Brain Ischemia diagnosis, Brain Ischemia etiology, Comorbidity, Constriction, Pathologic, Female, Humans, Intracranial Arterial Diseases complications, Intracranial Arterial Diseases diagnosis, Magnetic Resonance Angiography, Male, Middle Aged, Odds Ratio, Risk Factors, Severity of Illness Index, Antibodies, Antinuclear immunology, Disease Susceptibility immunology, Intracranial Arterial Diseases epidemiology, Intracranial Arterial Diseases etiology
Abstract

The prevalence of intracranial arterial stenosis (IAS) as well as antinuclear antibody (ANA) positivity was found to be higher in Asians than that in the Western population. To investigate the relation of ANAs with IAS in patients with acute ischemic cerebrovascular disease, we enrolled 2492 patients with acute ischemic stroke or transient ischemic attack into the study. All the patients were categorized into 3 groups according to the IAS burden. Multinomial logistic regression analyses were used in statistical analysis. The positive rate of ANAs in the IAS ≥ 2 group was higher than that in the single IAS group and the no IAS group (p<0.001). The adjusted odds ratio (OR) for IAS ≥ 2 in ANAs-positive patients was 3.737 (95%CI=2.676-5.220, p<0.001) compared with the ANAs-negative patients. ANAs were associated with multiple IAS rather than single IAS in both male and female subgroups. Besides, ANAs were significantly associated with single and multiple IAS in individuals ≤ 60 years. However, ANAs were only associated with two or more IAS in two age groups (between 61 to 75 years and >75 years old). In summary, ANAs are associated with IAS in patients with acute ischemic cerebrovascular disease.

Published
2020
Full Text
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