Search

Background: Adults suffering from schizophrenia and other psychiatric disorders report low levels of physical activity. In addition, these patients have an increased risk of overweight and poor nutritional habits. Less is known about patterns and levels of physical activity before the onset of disease., Aims: The purpose of the study was to investigate whether there were specific patterns of physical activity in the premorbid phase of schizophrenia and whether these participants differed from those with bipolar disorder (BD). A group of healthy controls (HC) was also included., Methods: The study was a prospective, longitudinal, comparative cohort design in which 15 adolescents who later developed schizophrenia and 18 with later BD were compared with HC. Data were analysed using non-parametric statistical tests., Results: Patients with a diagnosis of schizophrenia were less physically active with fewer days per week (p < 0.05) and fewer hours per week (p < 0.05) in the premorbid phase than both BD and HC. They also participated less in team sports than HC (p < 0.05)., Conclusion: Our results suggest that individuals who develop schizophrenia in their teens may be at risk of establishing a lifestyle harmful to health. From a preventive perspective it is important to gain more knowledge about the connections between health habits and later development of disease.

Background: The rates of remission of comorbid personality disorders for patients with a primary borderline personality disorder (BPD) have previously only been addressed in samples of inpatients or former inpatients with BPD receiving treatment-as-usual., Aims: The aim of the current study was to assess the rates of remission of comorbid axis II personality disorders in a sample of 32 outpatients with a primary BPD receiving open-ended non-manualized psychotherapy., Methods: Structured psychiatric interviews for DSM-IV were conducted by independent assessors at intake, discharge and 2-year follow-up. Independent t-test, chi-square and McNemar analyses based on intent-to-treat were used., Results: The overall rate of comorbid axis II disorders was significantly reduced from intake to 2-year follow-up. Patients with non-remitted BPD had significantly more PD diagnoses and symptomatic distress on all outcome measures at follow-up., Conclusion: Comorbid personality disorders among outpatients with BPD can be expected to remit with time and with remission of BPD. In the current sample of outpatients, comorbid paranoid, avoidant and obsessive-compulsive personality disorders at 2-year follow-up were associated with non-remitted BPD. The clinical implication of the results is that especially comorbid avoidant and obsessive-compulsive personality disorders may require specific attention in treatment of patients with BPD.

Background: Psychotherapy is an effective treatment for borderline personality disorder (BPD), but little is known about the long-term effect of non-manualized psychotherapy for these patients., Aims: The aim of the preliminary study was to investigate the long-term effect of non-manualized psychotherapy on an outpatient sample (n = 32) with a primary diagnosis of BPD., Methods: The current study was based on an open-ended naturalistic design with a 2-year follow-up. Assessment at intake, discharge and follow-up comprised the Structured Clinical Interview for DSM-IV Axis I, II and V, and the general level of self-reported symptomatic (SCL-90R) and interpersonal distress (IIP-64C)., Results: Patients with BPD respond well to non-manualized psychotherapy as intent-to-treat analyses estimate that 62% no longer met the DSM-IV criteria for a BPD diagnosis at discharge, 66% at 2-year follow-up. In addition, significant improvement with large effect sizes was found for all outcome variables at both discharge and at follow-up. Attrition was associated with patient-therapist gender mismatch, low occupational status and the presence of post-traumatic stress disorder., Conclusion: The results imply that the natural course of non-manualized psychotherapy is overall beneficial for outpatients with BPD.