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Three new monoterpene phenol dimers, bisbakuchiols V-X ( 1-3 ), and two bakuchiol ethers ( 4 and 5 ), along with four known compounds ( 6 - 9 ) were isolated from the fruits of Psoralea corylifolia . Their structures were elucidated based on extensive spectral analysis. The absolute configurations of 1 , 2 , 4 , and 5 were specified by quantum chemical calculations of ECD spectra.

Three new C-methylated phenylpropanoid glycosides (1, 2), a new 8-4'-oxyneolignan (3), together with two known analogs (4, 5), were isolated from the rhizomes of Imperata cylindrical Beauv. var. major (Nees) C. E. Hubb. Their structures were determined by spectroscopic and chemical methods. Compounds 1, 2, and 5 (10 μM) exhibited pronounced hepatoprotective activity against N-acetyl-p-aminophenol (APAP)-induced HepG2 cell damage in vitro assays. Furthermore, their antioxidant activities against Fe 2+ -cysteine-induced rat liver microsomal lipid peroxidation and the effects on the secretion of TNF-α in murine peritoneal macrophages (RAW264.7) induced by lipopolysaccharides were evaluated.

O-Methylmurrayamine A (7) and 7-methoxymurrayacine (8) are natural products isolated from Murraya koenigii and Murraya siamensis, respectively. In this paper, we report the synthesis of 7 and 8 which are featured in the key step of cyclization to form carbazole intermediate 5 with mild conditions. The structures were confirmed by 1 H NMR, 13 C NMR, and HR-ESI-MS. In addition, compounds 7 and 8 were tested for their neuroprotective effects against H 2 O 2 -induced PC12 cell damage. The results showed that compounds 7 and 8 have neuroprotective effect.