1. Fibrinogen as a potential diagnostic marker for prediction and evaluation of postpartum hemorrhage: a retrospective study.
- Author
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Zou Y, Jiang Y, Zhu D, Liu L, Zheng X, Gu X, Huang C, and Li L
- Subjects
- Female, Pregnancy, Humans, Fibrinogen, Retrospective Studies, Blood Coagulation, Vitamins, Postpartum Hemorrhage diagnosis, Hemostatics
- Abstract
Objective: To investigate whether prenatal fibrinogen (FIB) or other related factors could be utilized to evaluate the risk of postpartum hemorrhage (PPH)., Methods: A retrospective study was conducted in a database from January 2015 to December 2019. A total of 128 patients were enrolled and evaluated with FIB, in which 55 patients were assigned to low FIB and 73 in normal FIB., Results: According to the volume of blood loss, the mean of the low FIB group (<4 g/L) was markedly higher than that of the normal FIB group (≥4 g/L). Prenatal FIB was negatively correlated with PPH volume. The receiver operating characteristic (ROC) curve results indicated that the value of prenatal FIB was 0.701 to predict refractory PPH., Conclusions: Prenatal FIB was significantly related to thrombin time (TT), which may be an independent factor to predict the coagulation state of prenatal pregnancy.
- Published
- 2024
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