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In this study, complexes of kaempferol (KF) with polysaccharide arabinogalactan (AG) and disodium glycyrrhizinate (Na2GA) were prepared through mechanochemical technique to improve the solubility and bioavailability of KF. The physicochemical properties and the interactions of KF with AG/Na2GA were investigated through dissolution, SEM, XRD, and DSC studies. The reduction of particle sizes and destruction of crystal forms revealed the formation of solid dispersion which may have assisted the dissolution of the drug. The accelerated stability study showed higher stability for KF-Na2GA complex. In vivo pharmacokinetic study was performed to observe the plasma drug concentrations for KF complexes. Mechanochemical complexation of KF with AG/Na2GA improved the pharmacological activity as evident by the inhibitory potential of the complexes towards carbohydrate metabolic enzymes. In vivo studies were performed in STZ-induced diabetic mice, where the group treated with KF-AG complex showed better liver and kidney function and lower blood glucose levels than pure KF. Therefore, mechanochemical complexes of KF with polysaccharide or glycyrrhizate may serve as a promising formulation for the treatment of diabetes.

Inclusion complexes of salicylic acid (SA) and acetylsalicylic acid (aspirin, ASA) with polysaccharide arabinogalactan (AG) from larch wood Larix sibirica and Larix gmelinii were synthesized using mechanochemical technology. In the present study, we have investigated physicochemical properties of the synthesized complexes in solid state and in aqueous solutions as well as their anti-aggregation and ulcerogenic activity. The evidence of the complexes formation was obtained by nuclear magnetic resonance (NMR) relaxation technique. It was shown that in aqueous solution the molecules of SA and ASA are in fast exchange between the complex with AG macromolecules and solution. The stability constant of aspirin complex was calculated. It was shown that mechanochemically synthesized complexes are more stable when compared to the complex obtained by mixing solutions of the components. Complexes of ASA show two-fold increase of anti-platelet effect. It allows to reduce the dose of the antithrombotic drug and its ulcerogenic activity. These results substantiate the possibility to design new preparations on the basis of ASA with increased activity and safety.

(2005). An Experiment in Differentiated Instruction in a Higher Technical Educational Institution. Russian Education & Society: Vol. 47, No. 9, pp. 54-61.

A novel solid-phase mechanochemical method is being offered for synthesis of fluoroaromatic compounds from appropriate chloroaromatic derivatives, allowing for a decrease in process temperature and energy expenditure.

The interfacial tension in some normal alkane-water-sodium dodecyl sulfate systems has been measured with the spinning drop technique. The alkane scan of the data shows a deep minimum in the interfacial tension at dodecane as an oil phase. Simple explanation of this phenomenon based on the entropy of random mixing in the interfacial layer is proposed.

D. "URING THE PAST half century we have striven for the acceptance of community responsibility for Jewish education. Our contention was based on two principles: (a) that the education of all children is the concern of all the people, and (b) that despite ideological and organizational differentiation in a pluralist society, there are common unities, common essentials, which are basic to all educational programs of our people. We have insisted on "unity in diversity" and have argued that ways must be found for the ideological groups to share with a transpartisan educational community agency in the maintenance and supervision of schools, and in developing extra-curricular inter-group activities. We have contended that while recognizing the values of ideological commitment to particular programs, there are many important educational needs, many lacunae in a changing mobile society, which cannot be filled by individual institutions or by specialized groups. We have pointed to the waste, the parsimony, the low standards and the denigrating intolerance, resulting from isolationist divisiveness. We have urged that the concept of the Jewish people, the belonging and the devotion to it

(1966). A. P. Schoolman—The Story of a Blessed Life. Jewish Education: Vol. 36, No. 2, pp. 71-76.

* Opening Address at the Fortieth Annual Conference of the National Council for Jewish Education, Jerusalem, July 1966.

1 Report read at the Third Annual Jewish Education Dinner, Chicago Board of Jewish Education, at the Covenant Club, Chicago, June 10, 1929.

(1973). Israel and the Teaching of Jewish Identity. Jewish Education: Vol. 42, No. 2-3, pp. 21-26.

(1971). Brief Survey of Jewish School Work in Palestine. Jewish Education: Vol. 41, No. 1-2, pp. 26-36.

(1947). Aims of Jewish Education in the Diaspora. Jewish Education: Vol. 19, No. 1, pp. 6-13.

(1942). The Child and the Adult in Jewish Education. Jewish Education: Vol. 13, No. 3, pp. 165-169.

(1949). The Personality of Samson Benderly — His Life and Influence. Jewish Education: Vol. 20, No. 3, pp. 6-15.

*Editor's Note: This article is a reprint of the Summary of the Report of the Commission for the Study of Jewish Education in the United States, sponsored and published by the American Association for Jewish Education, 1959. For the complete Report of the Study, communicate with the American Association for Jewish Education. For an account of the organization of the Study of Jewish Education in the United States and the procedures followed in conducting the Study, see: Engelman, Uriah Z.: The First National Study of Jewish Education, JEWISH EDUCATION, Vol. XXIX, No. 1.

(1932). TWO DECADES OF PROGRESS IN JEWISH EDUCATION—A SURVEY. Jewish Education: Vol. 4, No. 1, pp. 3-13.