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2 results on '"Adebowale Benard Saba"'

1. Leaf extract of Anacardium occidentale ameliorates biomarkers of neuroinflammation, memory loss, and neurobehavioral deficit in N(ω)-nitro-L-arginine methyl ester (L-NAME) treated rats

Author

Ademola Adetokunbo Oyagbemi, Adedeji Kolawole Adebayo, Olamide Elizabeth Adebiyi, Kabirat Oluwaseun Adigun, Oluwabusayo Racheal Folarin, Oluwaseun Olanrewaju Esan, Temitayo Olabisi Ajibade, Blessing Seun Ogunpolu, Olufunke Olubunmi Falayi, Iyanuoluwa Omolola Ogunmiluyi, Temidayo Olutayo Omobowale, Olufunke Eunice Ola-Davies, James Olukayode Olopade, Adebowale Benard Saba, Adeolu Alex Adedapo, Sanah Malomile Nkadimeng, Lyndy Joy McGaw, Momoh Audu Yakubu, Evaristus Nwulia, and Oluwafemi Omoniyi Oguntibeju

Subjects
Health, Toxicology and Mutagenesis, Clinical Biochemistry, Biochemistry
Published
2023
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2. Naringin abrogates angiotensin-converting enzyme (ACE) activity and podocin signalling pathway in cobalt chloride-induced nephrotoxicity and hypertension

Author

Ademola Adetokunbo Oyagbemi, Temitayo Olabisi Ajibade, Oluwaseun Olanrewaju Esan, Moses Olusola Adetona, Ayobami Deborah Obisesan, Adewumi Victoria Adeogun, Omolola Victoria Awoyomi, Joseph Ayotunde Badejo, Aduragbenro Deborah A. Adedapo, Temidayo Olutayo Omobowale, Olayinka Israel Olaleye, Olufunke Eunice Ola-Davies, Adebowale Benard Saba, Adeolu Alex Adedapo, Sanah Malomile Nkadimeng, Lyndy Joy McGaw, Prudence Ngalula Kayoka-Kabongo, Momoh Audu Yakubu, Evaristus Nwulia, and Oluwafemi Omoniyi Oguntibeju

Subjects
Health, Toxicology and Mutagenesis, Clinical Biochemistry, Biochemistry
Abstract

The persistent and alarming rates of increase in cardiovascular and renal diseases caused by chemicals such as cobalt chloride (CoClForty-two male Wistar rats were randomly distributed to seven rats of six groups and classified into Group A (Control), Group B (300 part per million; ppm CoClCobalt chloride intoxication precipitated hypertension, renal damage, and oxidative stress. Immunohistochemistry revealed higher expression of angiotensin-converting enzyme (ACE) and podocin in rats administered only CoClTaken together, the antioxidant and metal-chelating action of Naringin administration against cobalt chloride-induced renal damage and hypertension could be through abrogation of angiotensin-converting enzyme and podocin signaling pathway.

Published
2022
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