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Biocompatibility of modified bionanocellulose (BC) and porous poly(ϵ caprolactone) (PCL) were compared to UHMWPE. For all the materials lack of cytotoxic effect to mouse fibroblasts was observed in vitro. In vivo study, subcutaneous implantations in Wistar rats, lasted for seven, 14, and 30 days. Subsequently the composition of surrounding tissue and explants surface changes was evaluated. No symptoms of acute inflammation were observed. Surrounding tissue thickness, the number of granulocytes, lymphocytes, macrophages, and blood vessels differed in time and revealed regular healing process. It is concluded that investigated PCL and BC are the materials with superior biocompatibility with high application potential.

Surgical gloves provide a protective barrier against blood-born pathogens. Studies reveal glove perforation rates of up to 45%, which are often unrecognized by the surgeon or nurse. The goal of this study was to evaluate how often glove perforation occurs after laparoscopic and open cholecystectomy.Gloves from the operating surgeon and the first assistant were collected after operation and tested immediately using two methods : 1. Water leak test - the approved standardized method to detect holes after filling up the gloves with 1000ml of water. 2. Electrical resistance test - method to detect gloves conductivity immersed in saline bath.Altogether, 376 gloves were studied. The overall perforation rate was 8%. Perforations more frequently were observed after laparoscopic than open cholecystectomy. The gloves worn by the operator were more likely to be perforated than those worn by the assistant surgeon in both types of operations. The most common site of perforation was in the index finger of the non- dominant hand. Thirty percent of gloves conducted electrical current, while 22% of them had no macroscopic evidence of perforation.Many of gloves might have microperforations that can not be detected using water leak test.