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27. Investigating the relationship between 25-hydroxyvitamin D and thyroid function in second-trimester pregnant women

Author

Shao Zhong, Yanjun Zeng, Qin Liu, Li-Wen Shen, Cai-Bo Wang, Bing Lu, Wen-hua Zhu, Ying Pan, and Xian-an Shen

Subjects
Adult, 0301 basic medicine, endocrine system, medicine.medical_specialty, endocrine system diseases, Endocrinology, Diabetes and Metabolism, Thyroid Gland, Thyrotropin, 030209 endocrinology & metabolism, Thyroid Function Tests, Positive correlation, vitamin D deficiency, Young Adult, 03 medical and health sciences, Elevated TSH, 0302 clinical medicine, Endocrinology, Pregnancy, Second trimester, Internal medicine, medicine, Humans, Vitamin D, 030109 nutrition & dietetics, business.industry, Obstetrics and Gynecology, medicine.disease, Thyroxine, Pregnancy Trimester, Second, Free triiodothyronine, Triiodothyronine, Gestation, Female, Thyroid function, business, Hormone
Abstract

This study aims to explore the correlation between serum 25-hydroxyvitamin D and thyroid hormones during the second trimester. In total, 277 pregnant women at 13-28 weeks of gestation were enrolled. According to the level of thyrotropic-stimulating hormone, they were divided into a reduced TSH group, a normal TSH group and an elevated TSH group. In this study, we found that the prevalence of vitamin D deficiency was as high as 94.58%. The 25-hydroxyvitamin D level in the reduced TSH group was lower than that in the normal thyroid function group (p = .0005), and the 25-hydroxyvitamin D level in the elevated TSH group was higher than that in normal TSH group (p=.0339). A positive correlation was observed between 25-hydroxyvitamin D and thyrotropic-stimulating hormone (r = 0.3034, p = .0000). Furthermore, 25-hydroxyvitamin D was negatively correlated with the free thyroxine level (r = -0.1286, p = .0323) as well as the free triiodothyronine level (r = 0.1247, p = .0380). These data suggest that the relationships between 25-hydroxyvitamin D and thyroid parameters were characterized during the second trimester. Pregnant women in the second-trimester who are diagnosed with transient hyperthyroidism should be evaluated for the possibility of vitamin D deficiency.

Published
2017

34. Reliability Analysis of Flexible Manufacturing Cells Based on Triangular Fuzzy Number

Author

Bo Tang Han, Chun Jie Xu, Cai Bo Zhang, and Chang Sen Sun

Subjects
Statistics and Probability, Design stage, Operations research, Fuzzy number, Production (economics), Fuzzy fault tree, Fuzzy logic, Reliability (statistics), Task (project management), Mathematics, Reliability engineering
Abstract

In most of flexible production schemes, the flexible manufacturing cells (FMCs) are more economical and feasible. So, an important task is to establish the correct reliability analysis model for the FMCs. However, with the increasing of system complexity, some reliability analysis modes can hardly describe the actual situation. Besides, due to the lack of test-data and field-data during the design stage of FMC' system, the reliability modeling will be more complicated. In order to deal with the deficient data and the uncertainty occurred from analysis and judgment, this article analyzes the reliability of FMCs system through the method of fuzzy fault tree, which is based on triangular fuzzy membership. At last, a practical example is illustrated. The reliability analysis model indicates that it can offer a diagnostic tool for FMCs system and improve the efficiency of operation and production in FMCs system.

Published
2006

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