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1. The impact of mitochondria-related POLG and TFAM variants on breast cancer pathomorphological characteristics and patient outcomes

Author

Rasa Ugenskiene, Domas Vaitiekus, Lina Poskiene, Elona Juozaityte, Jurgita Gudaitiene, Ieva Golubickaite, and Erika Korobeinikova

Subjects
Oncology, medicine.medical_specialty, business.industry, Health, Toxicology and Mutagenesis, Clinical Biochemistry, Distant metastasis, Cancer, Disease, 030204 cardiovascular system & hematology, Mitochondrion, TFAM, medicine.disease, Biochemistry, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, 030220 oncology & carcinogenesis, Tumor phenotype, Internal medicine, medicine, business
Abstract

Breast cancer is the most frequent female cancer, leading to relapse with distant metastasis of approximately one-third of patients. Cancer is usually considered a genetic disease involving mutatio...

Published
2021
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