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Your search keyword '"Ernesto Sánchez-Mendoza"' showing total 2 results
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2 results on '"Ernesto Sánchez-Mendoza"'

1. Steroidal saponin from Agave marmorata Roezl modulates inflammatory response by inhibiting NF-κB and AP-1

Author

Jonathan Cortés A, Renaud Condé, Alejandro Zamilpa, Lenin Domínguez-Ramírez, Elizur Montiel Arcos, Maribel Herrera-Ruiz, Manasés González-Cortazar, Eli Terán-Cabanillas, Julio César Almanza-Pérez, Ernesto Sánchez-Mendoza, and Jesús Enrique Jiménez-Ferrer

Subjects
chemistry.chemical_classification, Traditional medicine, 010405 organic chemistry, Inflammatory response, Organic Chemistry, Saponin, NF-κB, Plant Science, Biology, 01 natural sciences, Biochemistry, 0104 chemical sciences, Analytical Chemistry, 010404 medicinal & biomolecular chemistry, chemistry.chemical_compound, chemistry, Agave marmorata
Abstract

Agave marmorata Roezl is an endemic succulent specie from the Oaxaca-Puebla area of Mexico. This plant is a medicinal recourse and contain a rich variety of saponins-type compounds with multiples b...

Published
2020

2. Angiotensin-converting enzyme inhibitors from Salvia elegans Vahl

Author

Ernesto Sánchez-Mendoza, Ana Silvia Gutiérrez-Román, Natividad Giovana De la Cruz-Sanchez, Manasés González-Cortazar, Alejandro Zamilpa, Gabriela Trejo-Tapia, Maribel Herrera-Ruiz, and Enrique Jiménez-Ferrer

Subjects
chemistry.chemical_classification, biology, 010405 organic chemistry, Chemistry, Organic Chemistry, Lisinopril, Angiotensin-converting enzyme, Plant Science, biology.organism_classification, Mass spectrometry, 01 natural sciences, Biochemistry, 0104 chemical sciences, Analytical Chemistry, Terpene, 010404 medicinal & biomolecular chemistry, Enzyme, Phytochemical, Renin–angiotensin system, biology.protein, medicine, Salvia elegans, medicine.drug
Abstract

Phytochemical research of the acetate and methanol extracts of the aerial parts (flowers, leaves and stems) of Salvia elegans allowed to obtain seventeen known compounds (1-17): three of them (4, 5, 14), had already been described for this species, while the others (1-3, 6-13, 15-17) are described for the first time for S. elegans. All isolated compounds were characterized using spectroscopic techniques and mass spectrometry and were evaluated in the Angiotensin I-converting enzyme (ACE) inhibition model, where the phenolic compounds (13, 14 and 15) had the same inhibitory effect as lisinopril at 0.02 mg/mL. The terpenes showed a moderate inhibitory capacity at a concentration of 0.2 mg/mL.

Published
2020

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