Search

Cleaners have an elevated risk for the development or exacerbation of asthma and other respiratory conditions, possibly due to exposure to cleaning products containing volatile organic compounds (VOCs) leading to inflammation and oxidative stress. This pilot study aimed to quantify total personal exposure to VOCs and to assess biomarkers of inflammation and pulmonary oxidative stress in 15 predominantly Hispanic women working as domestic cleaners in San Antonio, Texas, between November 2019 and July 2020. In partnership with a community organization, Domesticas Unidas, recruited women were invited to attend a training session where they were provided 3M 3500 passive organic vapor monitors (badges) and began a 72-hour sampling period at which time they were instructed to wear one badge during the entire period ("AT", for All the Time), a second badge only while they were inside their home ("INS", for INSide), and a third badge only when they were outside their home ("OUT", for OUTside). At the end of the sampling period, women returned the badges and provided blood and exhaled breath condensate (EBC) samples. From the badges, 30 individual VOCs were measured and summed to inform total VOC (TVOC) concentrations, as well as concentrations of the following VOC groups: aromatic hydrocarbons, alkanes, halogenated hydrocarbons, and terpenes. From the blood and EBC samples, concentrations of serum C-reactive protein (CRP) and EBC 8-isoprostane (8-ISP) and pH were quantified. Data analyses included descriptive statistics. The 72-hour average of personal exposure to TVOC was 34.4 ppb and ranged from 9.2-219.5 ppb. The most prevalent class of VOC exposures for most women (66.7%) was terpenes, specifically d-limonene. Overall, most women also experienced higher TVOC concentrations while outside their home (86.7%) as compared to inside their home. Serum CRP concentrations ranged from 0.3-20.3 mg/dL; 8-ISP concentrations ranged from 9.5-44.1 pg/mL; and EBC pH ranged from 7.1-8.6. Overall, this pilot study demonstrated personal VOC exposure among Hispanic domestic cleaners, particularly to d-limonene, which may result from the use of scented cleaning products.

Scarcity of irrigation water, reduction in water quality, and increased amount of land affected by salinity are problems affecting production of dill (Anethum graveolens L.). A field experiment was...

Citrus peels are a rich source of nutrients, essential oil, and phenolic acid compounds. As they are produced in large amounts during fruit processing, these residues can be used as a potential nut...

Dancy tangerine trees have been imported from abroad and successfully cultivated in some newly reclaimed areas in Egypt. Reclamation areas (arid desert areas that are converted into areas suitable ...

The medicinal composition of rosemary essential oil has led to its widespread use in the food, cosmetic, health and herbal industries. In the present work, seasonal variations of essential constituents of essential oil, essential oil yield were evaluated. The predominant components of rosemary were: camphene, limonene, α-pinene, camphor, borneol, linalool, 1,8-cineole, (E)- caryophyllene and bornyl acetate. The highest rate of linalool was seen in summer, while camphor, limonene and borneol showed the highest percentage in cold season. Some of the compounds such as α-pinene, camphene, bornyl acetate and (E)- caryophyllene in the spring with the activation of some important plant enzymes such as peroxidase showed the highest amount. It is hoped that this research will provide very useful information about the best time to harvest the valuable rosemary plant and can be useful for the health, food and herbal industries that use this plant.

Citrus peel essential oils (EOs) have various biological activities such as antioxidant, anticancer, and antimicrobial. Growth location (GL) plays a physiological role in the formation of EO. This ...

Oral squamous cell carcinoma (OSCC) is the most common type of head and neck malignancy. Research on essential oils (EOs) has shown important cytotoxic and anti-tumor properties, among others. Piperaceae species are rich in EOs and here we highlight Piper rivinoides Kunth. We investigated the crude EOs from P. rivinoides, their pure major constituents and an enriched fraction with the main EO compounds (EF) as cytotoxic and selective OSCC agents. EOs presented as main compounds (-)-α-pinene, (-)-β-pinene and limonene. EOs showed an IC50 lower than all isolated compounds, except for (-)-β-pinene in OSCC cells. The (-)-β-pinene induced cell death with apoptotic characteristics. Commercial standards showed greater selectivity than EOs, and (-)-β-pinene was the most selective among them. EF showed higher selectivity compared to crude EOs and carboplatin, turning it into a good candidate as an anticancer fraction. These results are important for the possible development of new treatments for OSCC.

Citrus reticulata (Kinnow) peel essential oil, isolated major compound limonene and its derivatives were evaluated for their in vitro nematicidal activity against Meloidogyne incognita. The essenti...

In this study, the essential oil composition and antibacterial activity of the resin of Canarium strictum Roxb. was investigated. The oil was extracted by microwave-assisted extraction and analyzed...

In the present study, the chemical compositions of the essential oils from roots, stems, leaves and fruits of Foeniculum vulgare subsp. piperitum collected in Sicily were evaluated by GC and GC-MS. The main components of the roots were terpinolene (33.15%), gamma-terpinene (12.18%) and fenchyl acetate (11.23%). Stems and leaves were very rich in alpha-phellandrene (36.85% and 41.59%, respectively) and beta-phellandrene (19.68% and 25.79%, respectively), whereas the main components of fruits were terpinolene (20.10%) and limonene (17.84%)These results were compared with those of the EOs of the same vegetative parts of Foeniculum vulgare subsp. vulgare, collected in the same station and in the same days. The oils of F. vulgare subsp. vulgare showed completely different compositions, with estragole, (E)-anethole and alpha-pinene as main compounds, clearly indicating the differentiation of the two subspecies. Our results were also compared with those reported in literature for other accessions of Foeniculum vulgare subsp. piperitum[GRAPHICS].

The chemical composition of essential oils (EOs) isolated by hydrodistillation from Pterocarpus soyauxii Taub. root wood and root bark were determined for the first time by GC/MS analysis. The EOs ...

Context Pomelo peel oil (PPO) [Citrus maxima (Burm.) Merr. (Rutaceae)] is reported to possess antioxidant and antimelanogenic activities. Objective To investigate the effect of PPO [Citrus maxima (Burm.) Merr. cv. Shatian Yu] on tumour necrosis factor-α (TNF-α)-induced necroptosis in cerebral ischaemia–reperfusion injury (CIRI) after cardiac arrest (CA). Materials and methods Male Sprague Dawley rats were randomly assigned to six groups: sham group, PP0-L (10 mg/kg), PPO-M (20 mg/kg), PPO-H (40 mg/kg) and two control groups (CA, 0.9% saline; Gly, 10% glycerol). All drugs were administered intravenously to the CA/CPR rats within 10 min after return of spontaneous circulation (ROSC). After 24 h, rats were assessed for neuronal injury via the neurological deficit score (NDS), cerebral cortex staining and transmission electron microscopy (TEM) and expression levels of TNF-α and necroptosis-related proteins by immunoreactivity staining and western blotting. Results Compared to those in the sham group (survival rate, 100% and NDS, 80), the survival rate and NDS were significantly reduced in the model groups (CA, 56.25%, 70; Gly, 62.5%, 71; PPO-L, 75%, 72; PPO-M, 87.5%, 75; PPO-H, 81.25%, 74). In the PPO-M group, Nissl bodies were significantly increased (43.67 ± 1.906 vs. 17 ± 1.732), the incidence of pathomorphological injury was lower and the necroptosis markers (TNF-α, RIPK1, RIPK3, p-MLKL/MLKL) expression was downregulated compared to those in the CA group (p

Background Gastric ulcer is a prevalent disease with various etiologies, including non-steroidal anti-inflammatory drugs and alcohol consumption. This study aimed to explore the dual gastric protection effect of tadalafil and limonene as a self-nanoemulsifying system (SNES)-based orodispersible tablets. Methods Tadalafil-loaded limonene-based SNES was prepared, and the optimum formula was characterized in terms of particle size (PS), polydispersity index (PDI), and zeta potential (ZP) then loaded on various porous carriers to formulate lyophilized orodispersible tablets (ODTs). The ODTs were evaluated via determining hardness, friability, content uniformity, wetting, and disintegration time. The selected ODT was examined for its gastric ulcer protective effect against alcohol-induced ulcers in rat model. Ulcer score and ulcer index were computed for rats stomachs that were inspected macroscopically and histopathologically. Results The prepared SNES had droplet size of 104 nm, polydispersity index of 0.2, and zeta potential of −15.4 mV. From the different ODTs formulated, the formula with superior wetting time: 23.67 s, outstanding disintegration time: 28 s, accepted hardness value: 3.11 kg/cm2 and friability: 0.6% was designated. A significant gastroprotective effect of the unloaded and tadalafil-loaded ODTs was recognized compared to the omeprazole pre-treated group. Moreover, the histopathological analysis displayed very mild inflammation in the limonene-based ODTs group and intact structure in the tadalafil-loaded pre-treated animals. Conclusion Limonene gastroprotective effect functioned along with tadalafil in the form of SNES-incorporated ODTs could serve as a promising revenue for better efficacy in gastric ulcer prevention.

Changes of Valencia orange essential oils were evaluated under different agricultural locations (north, west and south) in Egypt. Essential oils of leaves, flowers and peels that were collected fro...

Grapefruit (GF) Citrus Χ paradisi Macfad (F. Rutaceae) is one of the major citrus fruits that encompass a myriad of bioactive chemicals and most unique among citrus fruits. Nevertheless, no study has yet to assess comprehensively its multitudinous constituents, health benefits, and valuable waste products. Hereto, the present review provides an updated comprehensive review on the different aspects of GF, its juice production, waste valorization, enhancement of its byproducts quality, and compared to other citrus fruits. Grapefruit uniqueness among other citrus fruits stands from its unique taste, flavor, and underlying complex chemical composition. Despite limonene abundance in peel oil and grapefruit juice (GFJ) aroma, nootkatone and sulfur compounds are the key determinants of its flavor, whereas flavanones contribute to its bitter taste and in conjunction with limonoids. Different postharvest treatments and juice processing are reviewed and in context to its influence on final product quality and or biological effects. Flavanones, furanocoumarins, and limonoids appear as the most prominent in GF drug interactions affecting its metabolism and or excretion. Valorization of GF peel is overviewed for its utilization as biosrobent, its oil in aromatherapy, limonene as antimicrobial or in cosmetics, fruit pectin for bioethanol production, or as biosorbent, and peel phenolics biotransformation. The present review capitalizes on all of the aforementioned aspects in GF and further explore novel aspects of its juice quality presenting the full potential of this valued multi-faceted citrus fruit.

In this study, the ultrasonic-assisted extraction (UAE) method is utilised for the extraction of carvone and limonene from the Mentha spicata species. The Box–Behnken design (BBD) is applied for fi...

The purpose of this study is to determine the chemical profile of the essential oils extracted from South African grown Citrus sinensis (L.) osbeck leaf and peels (fresh and dried) using gas chroma...

Dermatophytosis is a serious fungal infection of superficial keratinized tissue in man and animal. At least one million people in India were suffering from this infection. Present investigation dea...

Schinus polygamus (Anacardiaceae) is a shrub cultivated in Egypt for ornamental purpose. The major components of bark oil were dl-limonene (29.74%), followed by myrtenal (14.02%) and caryophyllene oxide (11.34%), while E-caryophyllene (55.86%), dl-limonene (27.71%) and β-pinene (3.54%) were predominant in the leaf oil. These isolated oils were screened for their antimicrobial activity against Staphylococcus aureus ATCC 33591, Staphylococcus aureus ATCC 29213, Escherichia coli ATCC 25922, Pseudomonas aeruginosa ATCC 10145, Candida albicans MTCC183 and Aspergillus niger NRRL 595, and two clinical isolates of Staphylococcus aureus. The leaf oil showed a remarkable inhibitory effect against all tested bacterial strains with minimum inhibitory concentration (MIC) range of 25 to 300 µg/mL, while the bark oil was active against Escherichia coli ATCC 25922 and Pseudomonas aeruginosa ATCC 10145 only. Furthermore, the bark and leaf oils revealed potent cytotoxic effects on HepG2 and Caco-2 cells with IC50 values of 1.56 to 24.12 µg/mL.

This work investigates the influence of ascorbic acid (ASA) on the essential oil (EO) isolated from leaves and peels of two Citrus species {Citrus deliciosa (Ten.) and Citrus tangerine (Hort. ex Ta...

Essential oil (EO) of Citrus has some biological and pharmaceutical properties; thus, it can be used in food and drug industries. Changes in growing seasons play important roles in physiological pr...

Glycerol monostearate solid lipid nanoparticles (SLN) were produced by hot high-pressure homogenization technique to load alpha-pinene, citral, geraniol or limonene. SLN were composed of 1wt.% monoterpene, 4wt.% of Imwitor® 900K as a solid lipid and 2.5wt.% of Poloxamer188 as a surfactant. Empty SLN consisted of 5wt.% of Imwitor® 900K and 2.5wt.% of Poloxamer188. The mean particles size (Z-Ave) and polydispersity index (PDI) of SLN were analyzed by dynamic light scattering (DLS), while the zeta potential (ZP) of each formulation were measured by electrophoretic light scattering. LUMiSizer® was applied to calculate the velocity distribution in the centrifugal field and instability index. Drug release profile from SLN was analyzed using Franz cell diffusion cells assayed by UVVis spectrophotometry, whereas the gas chromatography technique was applied to determine the encapsulation parameters of volatile monoterpenes. The matrix state, polymorphism and phase behavior of SLN were studied by X-ray diffraction (XRD, low and wide angles) and differential scanning calorimetry (DSC). Selected monoterpenes were successfully loaded in glycerol monostearate SLN. A burst release profile within the first 15min was observed for all formulations, being the modified release profile dependent on the type of monoterpene and on the encapsulation efficiency., The authors acknowledge the financial support received from Portuguese Science and Technology Foundation (FCT/MCT) and from European Funds (PRODER/COMPETE) under the project reference [M-ERA-NET/0004/2015-PAIRED and UIDB/04469/2020] (strategic fund), co-financed by FEDER, under the Partnership Agreement [PT2020]., info:eu-repo/semantics/publishedVersion

The peel’s essential oil of the Tunisian Citrus sinensis (L.) Osbeck var ‘Maltaise demi sanguine’ cultivated in six regions and three bioclimatic stages was analyzed by gas chromatography. Essentia...

Citrus limon L. Burmf (commonly known as lemon) is a small thorn bearing tree which belongs to the family Rutaceae cultivated in the tropical and subtropical regions of the world and mostly cultiva...

1. The aim was to evaluate the acaricidal effects of pure active components of essential oils against poultry red mite (Dermanyssus gallinae) as an alternative to chemical acaricides (organophospha...

The fruits of Zanthoxylum armatum DC. were collected from different altitudes (1000–2000 m) and populations (wild and cultivated) from Salyan district, Nepal. The essential oil was extracted by Clevenger apparatus and the components were analyzed through GC-MS. The yield of essential oil obtained from hydro-distillation of fruits ranged from 2.72 to 7.6%. The maximum yield was 7.6% from wild fruits at 1600–1800 m altitude and the minimum was 2.72% from cultivated fruits at 1000–1200 m altitude. This was the highest recorded essential oil yield from Z. armatum fruits. A total of 13 volatile compounds were identified from the essential oil by GC-MS analysis. The major components were linalool, cinnamate (E)methyl, limonene, myrcene, sabinene and terpinen-4-ol, which were present in higher proportion in all the samples. Other components were identified in a very low proportion. The main component linalool occurred in the highest proportion (74.12%) from wild populations at 1600–1800 m altitude and the lowest (44.73%) was from cultivated populations at 1000–1200 m altitude. The highest proportion of linalool was also reported for the first time in this study from Z. armatum fruits. Among the six major components of the essential oil, terpinen-4-ol was present in the lowest proportion. Results of the present study indicated that the altitude and habitat types could affect the essential oil composition in Zanthoxylum armatum fruits.

Stachys pilifera Benth is an endemic species of Iran where it is found in the mountainous habitats of Zagros region. The plant is a rich source of secondary metabolites endowed with different medicinal properties. Here, for the first time, the essential oil variability among eleven wild populations of S. pilifera, was investigated. Results indicated that the variation of the chemical profile of essential oils was remarkable. The most abundant components were cis-chrysanthenyl acetate (19.1-48.2%), viridiflorol (1.4-19.1%), trans-caryophyllene (2.3-11.9%), caryophyllene oxide (1.9-11.0%), limonene (2.0- 5.9%) and spathulenol (0.0- 9.5). Based on the cluster analyses (CA), four main chemotypes were recognized: chemotype I (cis-chrysanthenyl acetate), chemotype II (cis-chrysanthenyl acetate/viridiflorol), chemotype III (cis-chrysanthenyl acetate/viridiflorol/spathulenol), chemotype IV (cis-chrysanthenyl acetate/trans-caryophyllene/α-pinene). The chemical variation detected can be useful to consider these populations for pharmaceutical industries and industrial applications as well as for domestication and conservation purposes.

The chemical composition of Johreniopsis stricticaulis essential oil was obtained by hydro-distillation method from its aerial parts, and analyzed by gas chromatography-mass spectrometry (GC/MS).Totally the current essential oil was mainly constituted of sesquiterpene hydrocarbons. Germacrene-B (23.0 %)was the most abundant compound, and the other major compounds were α-cubebene (10.02 %), γ-elemene (5.37%) and limonene (4.72 %). Also antioxidant, antibacterial and antifungal activities of essential oil was tested.Antioxidant assay showed that the essential oil of J. stricticaulis has moderate activity, which was weaker thanpositive control butylated hydroxytoluene (BHT) (IC50 18.0 and 0. 13 mg/ml for essential oil and BHT,respectively). Moreover the essential oil of J. stricticaulis exhibited significant antibacterial and antifungalactivities against Staphylococcus aureus as well as Candida albicans, respectively; however, it had noantibacterial effects on Escherichia coli. These results proved that essential oil of J. stricticaulis includessesquiterpenes compounds with moderate antioxidant and antibacterial properties. This is the first report onchemical composition and biological activities of J. stricticaulis essential oil.

The orange peel (Citrus sinensis L.) from the variety Washington Navel was extracted by supercritical CO2 at different parameters. The extracts were analyzed by GC-MS and HPLC. Limonene predominance was found (up to 89%). The principal oxygenated monoterpenes were linalool, α- terpineol, decanal, and (E)- citral. From remaining solid residue (after SC-CO2 extraction) ultrasoundassisted extraction was performed to obtain the extracts rich in hesperidin. The influence of different extraction parameters on hesperidin content (3.3 to 23.0 μg/mL) was determined. The prediction performance in optimizing the extraction yield of dominant compounds was studied by response surface methodology and artificial neural network.

Breast cancer is the most common among women cancers and the most likely to cause death. Citrus plants essential oils are reported for having potential cytotoxic activities. Thirty three and thirty...

The present study aimed to evaluate the chemical composition of essential oil of Aegle marmelos (L.) grown in Western Ghats region. The hydrodistilled essential oil was analyzed by GC/MS and yield ...

The investigations was based on chemical diversity of the essential oils provide an opportunity to choose oils with preferential flavor and biologically active composition. Aerial part of F...

The yield and the composition of the peel essential oils (EO) of six new citrus hybrids obtained from the crosses between Murcott tangor—TM [Citrus reticulata Blanco x Citrus sinensis (L.) ...

Essential oils from six plant species that occur in the north part of Alexandria governorate, Egypt, were extracted by hydrodistillation in a Clevenger-type device. The chemical compositions of the essential oils were analysed using gas chromatography-mass spectrometry. The essential oils were tested for their toxicities towards the adults of Tetranychus urticae by contact and fumigant methods. The essential oils were also tested for their inhibitory effects on acetylcholinesterase of T. urticae adults. The results of GC-MS analysis showed that monoterpenes were the dominant class of compounds in all essential oils. The compounds 1,8-cineole (71.77%), limonene (74.29%), pulegone (77.45%), α-pinene (35.49%), β-citronellol (35.92%) and terpinen-4-ol (20.29%) were the major components of the essential oils from Calistemon viminals, Citrus paradisi, Origanum vulgare, and Thuja orientalis, and Cupressus macrocarpa, respectively. The acaricidal activities against T. urticae varied depending on the assay method employed, tested essential oil and exposure time. In general, the essential oils were more toxic to T. urticae using fumigation method than contact method. Also, the contact toxicity was higher after 48 h of treatment than 24 h. The essential oil of C. macrocarpa (LC₅₀ = 5.69 mg/L air) caused the highest fumigant toxicity, while the essential oil of O. vulgare (LC₅₀ = 67.89 mg/L) was the most effective in contact toxicity. In addition, the tested essential oils showed remarkable inhibition on the activity of T. urticae AChE indicating that the mortality of the mite may be attributed to the inhibition of AChE. Based on the results of the current study, it can be noticed that the tested essential oils possess a potential to be used as alternatives for synthetic pesticides for controlling T. urticae.

There are two chemotypes of Litsea cubeba (Lour.) Pers. (fam. Lauraceae) essential oils (EOs), either dominated by citral and limonene or by citronellal. L. cubeba EOs exhibits broad antimicrobial ...

Benzoic acid (BA) plays an important role in physiological processes of Valencia orange essential oil. The essential oil of Valencia orange has different medicinal and biological properties...

Sweet mint plants (Mentha spicata) were separately exposed to blue, red and green light emitted diodes (LED) lights and natural sunlight as a control. Leaves were analyzed periodically for their essential oil composition using head space GCMS analysis. Control experiments showed that the main essential oil components were carvone (80%), limonene (17%) and other minor terpenes (3%). Exposed plants to green and red lights showed that their headspace essential oils were similar to that of the control plants. However, blue LED lights caused complete disappearance of carvone and limonene, which were never recovered. Disappearance of carvone and limonene were associated with the appearance of new chemicals at concentrations of 65 and 21% that were identified as carvone oxide and eucalyptol, respectively.

The chemical composition and antioxidant activity of the essential oil from the stems of Bursera graveolens (Kunth) Triana et Planch grown in Manabi (Ecuador) were studied. Ninety-nine compounds we...

Variation in the composition of leaf essential oils of Zanthoxylum armatum in relation to altitude and soil chemistry was analyzed in Nepal. The essential oil was extracted by Clevenger apparatus and the components were analyzed through GC-MS. The results showed that: Yield of the essential oil obtained from the hydro-distillation of dried leaves ranged from 0.16% to 0.50%. GC-MS analysis revealed total of 17 compounds in the essential oil from the dried leaves of Z. armatum from different altitudes and populations (wild and cultivated). The three major components, linalool, limonene and undecan-2-one, present in higher proportion in all the samples were analyzed. Other components tridecan-2-one, myrcene, cinnamate(E)-methyl and alpha-bergamotene were also identified in most of the samples but in lower proportions. The highest number of components (12) was identified from the wild samples collected from 1990 m and the lowest number (7) was from 1060 m (wild) and 2030 m (cultivated populations). Linalool, a major component was found in higher amount (64.88%) at the lowest altitude of 1060 m. Results of the present study showed that the altitude, soil chemistry, and growing conditions significantly affect the essential oil components in Zanthoxylum armatum.

Essential oil of grapefruit used in various food and drug industries. Previous investigators indicted that salicylic acid and different locations had a significant role in essential oil pro...

Cupressus atlantica Gaussen is an endemic and threatened forest tree mainly located at the western High Atlas Mountains of Morocco. This study is a pleading for protection and restoration of this particular Mediterranean cypress species, through the characterization of chemical variability of its essential oils (EOs) and their recovery in different fields, especially as protective treatment against wood decaying fungi. Composite samples of leaves, twigs, and cones were collected within five populations. Sapwood and heartwood sawdust oils were also analyzed. EOs were extracted by hydrodistillation and analyzed by GC-MS. C. atlantica oils are characterized by high chemical variability between types of biomass and populations. Thus, leaves and twigs oils are dominated by hydrocarbon monoterpenes; those of wood by oxygenated monoterpenes and oxygenated sesqueterpenes, and those of cones by hydrocarbon monoterpenes and sesquiterpenes. Three chemical profiles have been identified in leaves oils within s...

The essential oils (EOs) of Ammodaucus leucotrichus fruits collected from four regions in Algerian Sahara were investigated for their chemical components, oil yield diversity and antibacterial property. Furthermore, the anti-inflammatory activity and the acute toxicity of these oils are herein reported for the first time. The hydrodistillated oils yielded (2.82-3.87 %) (w/w). GC and GC-MS analyses allowed us to identify twenty components representing (95.6-99.4 %). The main components were perillaldehyde (63.6-87.7 %), limonene (7.3-19.4 %) and α-pinene (1.2-7.9 %). The determination of the acute toxicity effect in mice showed the slight toxic nature of the EOs (LD50: 520-570 mg/kg). The oils exhibited significant anti-inflammatory effect; the inhibitions at a dose of 100 mg/kg were (18.7-24.5 %). Based on the determination of inhibition diameters, a high antibacterial activity against yeasts and gram-positive bacteria strains and a moderate activity against gram-negative bacteria strains were obs...

Although several studies show that Schinus terebinthifolius Raddi fruits are a promising source of bioactive compounds, few studies have investigated the anticancer activity of its essential oil (EO). The objective of this study was therefore to investigate the antiproliferative activity of S. terebinthifolius fruit EO against eight human tumor cell lines. A central composite rotatable design with 11 experiments was developed to investigate the optimal conditions of hydrodistillation by Clevenger apparatus. EO obtained at optimized conditions (yield greater than 6.7%) showed potent activity for all cell lines investigated; the most promising results were observed against leukemia, kidney, multidrug-resistant ovarian, and prostate tumor cell lines. Gas chromatography-mass spectrometry revealed the following major compounds in the EO: δ-3-carene (33.78–36.73%), α-phellandrene (15.67–17.30%), limonene (15.03–16.32%), α-pinene (7.03–9.20%), and germacrene D (4.98–6.99%). Future work involving fractionation of the EO might shed some light on the compounds responsible for each antiproliferative activity.

The compositions of essential oils from the leaf, stem and fruit of Neolitsea buisanensis Yamam. & Kamik. from Vietnam were reported. The essential oils were analysed by gas chromatography (GC) and...

Anethum graveolens is cultivated since ancient times as a vegetable, aromatic, carminative and antispasmodic in Iran. This field experiment was conducted in the form of factorial experiment based on randomized complete blocks design. Treatments were at four levels of nitrogen rates (control, 50, 100 and 150 kg.ha-1) that used in the form of urea fertilizer. The effect of N fertilizer on height plant, biological yield and the essential oil percentage of Dill and its correlations was determined. The essential oil of Dill was obtained by hydro distillation method for 2 hours and then the composition of essential oil was determined by GC-MS. The results indicated that the highest biological yield obtained at N (150 kg/hr). The essential oil yield was 2.00-2.25% (v/w). Seventeen compounds were identified and α-phellandrene (49.54%), p-cymene (18.19%), Limonene (13.79%) and β-phellandrene (9.00%) were the major component of the essential oil.

Variation in essential oil composition of isolated leaves, isolated stems and leaves + stems of Haplophyllum tuberculatum was studied at the three developmental stages during a one-year phenological cycle. GC–MS analysis showed qualitative and quantitative variation over the phenological cycle. The main components were limonene (7.35–14.34%), α-phellandrene (7.14–11.87%), 2,4-bis(1,1-dimethylethyl)-phenol (2.52–11.56%), trans-p-menth-2-en-1-ol (7.46–10.83%), δ-3-carene (8.33–10.41%), piperitone (2.33–9.42%) and myrcene (4.91–8.25%), where their percentages varied according to the developmental stage of growth. The results from HCA and PCA revealed a clear discrimination between the three studied developmental stages. Essential oils at flowering and fruiting stages showed higher antimicrobial activity than those at vegetative stage. The highest antioxidant activity was also exhibited by essential oils at flowering and fruiting stages. The present findings allowed choosing the best organ with the op...

As a medicinal and industrial plant, Myrtle (Myrtus communis L., Myrtaceae) is widely used in pharmacological, food, and cosmetic industries. In the current study, variabilities in the leaf essential oil (EO) compositions of 23 Myrtle populations, collected from the natural habitats of different regions in Fars Province, Iran, were studied. The EO yields of the populations varied from 0.53% to 1.75% based on dry matter. According to GC/MS analysis, α-pinene (12.2–60.4%), 1,8-cineole (6.2–27.3%), limonene (1.4–26.7%), linalool (0.7–21.0%), myrtenyl acetate (0–29.1%), and geraniol (0.3–8.3%) were the major compounds. Using the hierarchical cluster analysis, the myrtle populations in Fars province were classified into four groups based on the main EO components, namely I α-pinene/1,8-cineole, II α-pinene/1,8-cineole/linalool, III α-pinene/limonene/1,8-cineole and IV myrtenyl acetate/limonene/linalool. In conclusion, this study gave new insights into the breeding programs for obtaining potential plant...

The aim of present study was to investigate chemical compositions and in vitro antioxidant activity of essential oil (EO) from Coreopsis tinctoria Nutt flower obtained in Huocheng County of China. ...

Gas chromatographic analysis of Citrus tachibana (Makino) Tanaka peel essential oil showed that the volatile composition contained 111 components including monoterpenes, sesquiterpenes and oxygenat...

The essential oils compositions from different parts of Pituranthos tortuosus (Coss.) Maire collected at the flowering and the fruiting stages were investigated. The essential oils were extracted by hydrodistillation and analyzed by GC/FID and GC/MS techniques. A total of 53 compounds representing 95.7 to 99.6% of the total oil were identified, showing large qualitative and quantitative differences. The analyzed oils were characterized by a very high percentage of monoterpenes, in which the monoterpene hydrocarbons constituted the predominant class especially in the stems (79.1%) at the fruiting stage. The major compounds in the flowers and the seeds were dillapiole (33.9; 37.2%), limonene (14.9; 10%), sabinene (8.8; 10.9%) and 3- n-butylphtalide (14.2; 6.7%), respectively. The antioxidant activity of the essential oils was evaluated by the metal (Fe2+) chelating and Fe3+ reducing power assays. The stems and seeds essential oils showed an important reducing power (EC50 : 0.06-0.08 mg/ml). Our find...