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The study aimed to evaluate the impact of the dual trigger with the combination of GnRH agonist and standard dose of recombinant hCG on IVF outcomes in poor ovarian responders with GnRH antagonist protocol. 1283 cycles of 1010 poor responder patients according to Bologna criteria were retrospectively analysed in terms of final oocyte maturation: dual trigger group (250 mu g hCG + 0.2 mg triptorelin) or standard group (250 mu g hCG). Primary outcome measures were the number of retrieved and mature oocytes. The secondary outcome measures were clinical pregnancy rates and live birth rates. The number of retrieved oocytes, mature oocytes, and the top-quality embryos transferred were significantly higher in the dual trigger group (p < .001). Fertilisation rates (73.6% vs 69.6%, p = .009), implantation rates (18.7% vs 14.6, p = .039), clinical pregnancy rate per embryo transfer (27.5% vs. 19.9%, p = .010) and live birth rate per embryo transfer (21.6% vs. 14.9%, p = .011) were also significantly higher in the dual trigger group as compared to the hCG trigger group. The usage of dual trigger with a GnRH agonist and a standard dosage of hCG could improve clinical pregnancy rates and live birth rates in poor ovarian responders undergoing GnRH antagonist IVF/ICSI cycles.IMPACT STATEMENT What is already known on this subject? Dual trigger with standard dose of hCG has been the subject of trials in normal responders to optimise IVF outcomes. The results of these studies showed significant improvements in implantation and pregnancy rates with an increase in the number of mature oocytes retrieved. As a result, dual trigger has become a popular ovulation trigger option in GnRH antagonist cycles. What do the results of this study add? There is limited data about the use of dual trigger in poor ovarian responders (PORs). According to our study, increasing the number of retrieved oocytes, mature oocytes, the number of fertilised oocytes, the number of transferred embryos and top quality embryos transferred by using dual trigger in patients with PORs have a positive impact on pregnancy outcomes. What are the implications of these findings for clinical practice and/or further research? These findings implies potential advantages of dual trigger usage for improving IVF outcomes in PORs. With large sample sized prospective randomised trials, dual trigger with combination of GnRHa and a standard dose of hCG might replace the traditional ovulation trigger with hCG in PORs.

In this study, thickness of single- and multi-layer nonwoven glass fiber fabric in dry and wet state was monitored during compaction and relaxation periods under a pressure range of 2 to 200 kPa. T...

This study aims to explore the construct of Mobile Dependency (MD) by distinguishing its sub-dimensions and to identify and verify hospitality employee clusters with respect to their MD. Investigat...

Purpose: To evaluate whether G-CSF improves the endometrial thickness of thin endometrium by influencing proliferative, angiogenic and apoptotic factors, an experimental rat model was conducted using 24 female adult rats with either thin or healthy endometrium that each was further divided into G-CSF or saline injection groups with six rats. Materials and methods: After forming of the thin endometrium by uterine injection of 0.2 ml 96% ethyl alcohol to the rats, five days of subcutaneous injections of 40 μg/kg G-CSF or saline were given. Endometrial thickness, immunohistochemically expression of vascular endothelial growth factor receptor-2 (VEGF-R2), proliferative cell nuclear antigen (PCNA) and fibronectin apoptosis with TUNEL method were compared in specimens among four groups of post-model rats. Results: Endometrial thickness was significantly improved in thin but not in normal endometrium group with GCSF when compared to saline injection. Stromal and glandular epithelial expression of PCNA and pericapillary VEGF-R2 was significantly increased, and apoptosis was significantly decreased with G-CSF. Although fibronectin was also increased with G-CSF in the thin endometrium, the difference was non-significant. In further, G-CSF decreased apoptotic cells and increased expression of PCNA when compared to saline injection in normal endometrium. Conclusions: G-CSF improves endometrial thickness, proliferation, angiogenesis and DNA fragmentation in thin endometrium. © 2020 Informa UK Limited, trading as Taylor & Francis Group.

The purpose of this study was to investigate the effect of homocysteine (Hcy) on CD36, PPARγ, and C/EBPα gene and protein expression in adipose tissue obtained from normal and high-calorie diet obesity models. CD36, PPARγ, and C/EBPα gene expression and protein levels in adipose tissue specimens were determined using the RT-PCR and ELISA methods, respectively. Significantly increased CD36 gene expression was observed in adipose tissue from obese mice, while Hcy significantly reduced CD36 gene expression in adipose tissue from normal and obese mice. PPARγ and C/EBPα gene expression levels decreased significantly in all groups compared to the normal group. In addition, levels of both PPARγ and C/EBPα gene expression were lower with Hcy supplementation compared to their own controls. In conclusion, Hcy's reduction of CD36 gene expression in adipose tissue may be one probable factor in hyperhomocysteinemia representing an independent risk factor for cardiovascular diseases.

Occupational diseases cause an important burden on health and economy; however, they are substantially underestimated. We aimed to investigate the opinions of physicians about causes of underreporting of occupational diseases. We collected data with a questionnaire, listing 30 possible causes for underreporting of occupational diseases. 478 physicians participated in the study. The first 3 most frequent causes perceived as "very important" are; employers' perception of occupational safety and health services as a loss of revenue (64.9%), prevalent employment without a legal contract (64.6%), and prevalent employment as subcontracted (59.4%). 52.1% of the physicians worked or currently working as an occupational physician. With the increase of working year as an occupational physician, there was a statistically significant decrease in the strength of importance for 17 of the 30 statements. This finding may be one of the important causes of underreporting of occupational diseases.

In this study; the effects of loop, skip, and tuck stitch types, and weft-inlay yarn, on air permeability and bursting strength of weft-knitted fabrics from glass yarn were revealed. Due to...

In this study, a mixture apricot and peach stones, and almond shell, which are hard-shelled agricultural wastes, was evaluated as a precursor for activated carbon synthesis. Effects of the impregna...

This study revealed the effect of cam setting and number of yarn ply on air permeability and bursting strength of weft-knitted fabrics from glass yarn. Change in cam setting from loose to tight level increased fiber content, and stitch-density; while it decreased loop length. Fabrics with 3-ply yarn exhibited higher fiber content; lower stitch-density; and longer loop length than fabrics with 2-ply yarn. Cam setting showed more pronounced effect on physical properties of fabric than number of yarn ply. Fabrics knitted via tight cam setting level exhibited less air permeability, and higher bursting strength than fabrics knitted via loose cam setting. Fabrics from 3-ply yarn showed less air permeability and higher bursting strength than fabrics from 2-ply yarn. Loop length, wale density, and fiber content were determined as the most effective physical properties on permeability and bursting strength. A negative correlation was detected between air permeability and bursting strength.

The incidence of occupational diseases (ODs) is below expectations. The approaches of family physicians are very important. In this study, we aimed to evaluate attitudes and behaviors of family physicians about ODs.The questionnaire was first sent to family physicians via e-mail. Of 3663 responders, 3090 replies were included to study.44.1% of them stated they obtained detailed occupational history. In logistic regression analysis, physicians who obtained detailed occupational history, discussed their patient's health with an occupational physician, had education about ODs and those who stated that they wanted to receive training in ODs were more likely to refer their patient.In this study, it was determined that those who received education on ODs and those who have worked as workplace physician obtained occupational history, knew occupational diseases hospitals and wanted to receive further education.

This study aims to examine the potential effects of three revenue management pricing strategies (best rate guarantee, rate (dis)parity, and rate frame) on customers’ perceived fairness. A 2 × 2 × 2 factorial between-subjects experimental design was used. Eight scenario-based surveys were employed to evaluate how potential hotel guests react to three different revenue management strategies. The outcome of this study offers a set of guidelines for hoteliers to follow in terms of revenue management pricing strategies across multiple distribution channels, while providing revenue managers with empirically supported suggestions to increase hotel revenue.

The main purpose of the current article is to investigate the status of the usage of Twitter-marketing and to examine the potential factors that impact the usage of Twitter-marketing. The results show that 69.4% of the multi-unit restaurant companies studied use Twitter-marketing and that small restaurants are more likely to utilize Twitter-marketing.

This study aimed to evaluate the effect of luteal phase support on clinical pregnancy and live birth rates after ovulation induction and intrauterine insemination (IUI).579 cycles from 2010 to 2013 were retrospectively evaluated. Ovarian stimulation was performed with gonadotropins, and rHCG was used for ovulation triggering. All patients received IUI. 451 cycles were supported by receiving vaginal micronized progesterone capsules (142 cycles) or vaginal progesterone gel (309 cycles) whereas 128 cycles were not supported.Clinical pregnancy (20.6 versus 9.4%; p = 0.004) and live birth rates (14 versus 7%; p = 0.036) were higher for supported group than for unsupported group. Progesterone gel and micronized progesterone subgroups achieved similar clinical pregnancy and live birth rates (21.4 versus 19%, p = 0.567 and 14.2 versus 13.4%, p = 0.807; respectively).Luteal phase support improved the success of IUI cycles affecting both clinical pregnancy and live birth rates when gonadotropins were used for ovulation induction. The use of vaginal progesterone gel or micronized progesterone significantly improves clinical pregnancy rates. The live birth rates were higher in the progesterone gel group, but were similar in the micronized progesterone group compared to the unsupported group.

This study analyzes hospitality faculty position announcements that were published in the Council on Hotel, Restaurant, and Institutional Education Communique during the period of spring 2006 to spring 2010. It also considers the impact of the economic downturn on the job market for hospitality educators in the United States during this period and further examines available data beyond the downturn. In comparison with past trends, the results indicate that the period of economic downturn and its aftermath possibly had a major identifiable impact on the quantity of hospitality faculty position announcements. Regardless, the findings show a pattern of growing demands on faculty selection criteria. An increasing number of jobs announced during this period required a terminal degree (Ph.D.), teaching experience in two or more subject areas, and relevant industry experience. The emphasis on research experience emerged as a relatively new criterion when compared with the findings of past similar studies.

Through the thickness mechanical properties of composites have been improved with the advance of 3D woven preforms incorporating through-thickness reinforcement element compared to 3D woven composites from stack of 2D fabrics. In this study, a generalized geometric model considering non-jammed and jammed constructions of 3D orthogonal woven preforms from spun yarns was developed to predict fiber volume fraction (FVF) of structure constituents, preform thickness, preform areal density, and minimum thread spacing (x-, y-, and z-yarn spacing) to achieve jammed construction in terms of weave factor, number of layers, and constituents’ variables (y- and z-yarn sequence, linear densities, packing factor, and fiber volumetric density). Numerical results are presented to demonstrate the generalized model potential as a design tool to achieve broad range of constituents FVF that controls composite performance.

1. The aim of the study was to examine the morphology of the tongue and the histochemical features of the lingual salivary glands in this species. 2. The tongue was elongated, terminating in a rather sharp, dagger-like apex. On the surface of the tongue and situated between the body and root of the tongue, two rows of conical papillae, the sharp apices of which pointed towards the posterior part of the tongue, were observed. The keratinised epithelium lining the dorsal surface lacked typical gustatory papillae. However, it was observed that taste buds were present in the epithelium of the lingual body and root. The tongue was supported by a structure composed of hyaline cartilage, the paraglossum, which extended from the lingual root to the apex. Simple branched tubular glands, which were encapsulated by connective tissue, were embedded within the submucosa in the body (anterior salivary glands) and root (posterior salivary glands) of the tongue. It was observed that the secretion of the lingual glands contained neutral mucins, proteoglycans containing carboxylic acid, weak and strong sulphated groups, N-acetylated sialomucins, but lacked glycogen. 3. It was demonstrated that, the general morphological features, papillary distribution of the tongue and the histological structure of the mucosa epithelium and the supportive elements displayed similarity to those of other domestic avian species. It was also determined that, in view of the particular feeding types, in the partridge, the presence of the papillary crest was not correlated with diet.

Technology is a critical determinant in hotel guest satisfaction. Hotels often utilize technology as a value-added amenity to help promote differentiation and enhance guest satisfaction. The purpose of this study was twofold: to measure and document the level of guest satisfaction with existing technology-based amenities, and to examine the scope of impact of such amenities on overall hotel guest satisfaction. A random sample of 3,000 American travelers was chosen from a national database for this study. A total of 534 usable responses were received. The results indicate that there is a significant positive relationship between three factors—“Business Essentials for Travelers,” “In-Room Technologies,” “Internet Access”—and hotel guest's overall satisfaction. “Comfort technologies” factor was found not significant in predicting hotel guest's overall satisfaction.

To investigate the effect of intranasal estrogen replacement therapy administered to postmenopausal women alone or in combination with progesterone on markers of cardiovascular risk.The study was conducted with 44 voluntary postmenopausal women. In group I (n = 15), the patients were treated with only intranasal estradiol (300 μg/day estradiol hemihydrate). In group II (n = 11), the patients received cyclic progesterone (200 mg/day micronized progesterone) for 12 days in each cycle in addition to continuous intranasal estradiol. Group III (n = 18) was the controls. Serum lipid profiles, oxidised low-density lipoprotein (LDL) and other markers of cardiovascular risk were assessed at baseline and at the 3rd month of the treatment.Lipid profile, LDL apolipoprotein B, lipoprotein a, homocysteine, oxidised LDL values and oxidised LDL/LDL cholesterol ratio were not observed to change after 3 months compared to baseline values within each group (p0.016). In comparison to changes between the groups after the treatment, only oxidised LDL levels and oxidised LDL/LDL cholesterol ratios of group II were increased compared to control group (p0.05).Intranasal estradiol alone did not appear to have an effect on markers of cardiovascular risk in healthy postmenopausal women. However, the addition of cyclic oral micronized progesterone to intranasal estradiol influenced the markers of cardiovascular risk negatively in comparison to non-users in healthy postmenopausal women.

The aim of our study was to determine the distribution of estrogen receptor α (ERα) and progesterone receptor B (PR-B) in the bovine oviduct during the follicular and luteal phases. Bovine oviducts from 23 animals were obtained from a local slaughterhouse. Blood samples from these animals also were taken before death to measure estrogen and progesterone levels. The serum levels of estradiol-17β and progesterone changed during the estrous cycle. Tissue distribution of ERα and PR-B was examined using immunohistochemical techniques and the results showed that ERα and PR-B were stained in nuclei of cells and could be detected in all compartments along the entire oviduct during both the follicular and luteal phases. During the follicular phase, no significant differences were found between ERα and PR-B distribution (p < 0.05), while significant differences were found between ERα and PR-B during the luteal phase (p < 0.05). We results indicated that the frequency and intensity of ERα and PR-β immunoreactivity in the oviduct of bovines varied according to the oviductal cell types and the phases of the sexual cycle.

This study offers a unique application of gap analysis as a diagnostic tool to examine slot players' perception of customer service and the quality of their gaming experience. As part of the gap analysis, an importance-performance matrix was designed to visually depict significant measures according to whether or not these measures met slot players' expectations. It was discovered that several service and quality related issues lacked in terms of perceived performance by patrons of the casino that was examined in this current study. The results of this study will help casino management identify critical factors affecting slot players' overall gaming experience and thus, allocate resources effectively to the areas for improvement.

The practice of brand positioning by label or name, and creating an image in the minds of patrons, is common in the hospitality industry. Nevertheless, the process of establishing market awareness along with creating product identity is challenging, particularly in the entertainment segment of the hospitality industry where theme-based positioning is popular. This study undertakes a systematic analysis of identifying key subjective dimensions for labeling a theme-based hospitality operation. The focus of the study was a uniquely located lounge atop a casino/hotel tower in Las Vegas, Nevada. The study identified theme and attraction-based attributes among potential patrons utilizing perceptual mapping.

Although the number of U.S. hospitality graduate programs has increased over the past two decades, few research studies have addressed how hospitality graduate education is perceived by its stakeholders: students, educators, and employers. This study offers a multidimensional framework to assess the status quo of hospitality graduate education. General management skills, curriculum, generalist and specialist approaches, and effective teaching methods were investigated through three perceptional dimensions; hospitality industry professionals, educators, and students. The results confirm several significant gaps and intriguing differences among the stakeholders' perceptions of graduate education in hospitality. Implications of these important findings are discussed.

The purpose of this study was to examine the impact of employee relations programs (ERP) on organizational performance in the lodging industry. ERP provides employees with opportunities to participate in planning and improving work-related tasks. Four items were used to measure employee relations: formal complaint-resolution programs, participation programs, attitude surveys, and suggestion systems. Further, three types of organizational performance measures, namely employee turnover, labor productivity, and revenue per available room (RevPAR) were used. Findings indicated that ERP led to higher labor productivity and RevPAR.

Massive ovarian oedema is an unusual clinical entity occurring in teenage girls. It is a rare tumour-like condition of the ovary characterized by marked enlargement of one or both ovaries due to marked accumulation of oedema fluid in the ovarian stroma. Massive ovarian oedema may result from partial or intermittent torsion of the mesovary, interfering with venous and lymphatic drainage, but not with arterial blood flow. The patients most commonly present with lower abdominal pain and enlargement. This entity can clinically mimic a neoplasia. We report three cases with massive ovarian oedema.

This study attempts to determine the effects of music genre and intensity on patron's ethnic menu item selection at a military dining facility in the Southwestern United States. The experiment was conducted during six two-hour lunch periods. Eight hundred and fifty eight responses were collected. A modified Mehrabian-Russell Model was used as the experimental design. Fixed effects multinomial logistic regression (MLR) was used to analyze the data. It was discovered that the presence of ethnic music has a significant effect on the selection of ethnic entrees. Specific levels of music intensity of an ethnic genre were also found to have a significant impact on ethnic menu item selection. Finally, several moderating variables-age, gender, and general likings for the ethnic meals-significantly affected the relationship between music genre and intensity on ethnic menu item selection.

The Internet has had an undeniable impact and influence on hospitality industry. Within the last decade, the introduction of Web 2.0 has fashioned countless opportunities for hospitality organizati...

This study deals with the removal of Cr(VI) from aqueous solutions by using filter cake known as zinc extraction residue (ZER) generated as a by product in a zinc production plant located in Kayseri-TURKEY. It was found that ZER, which is rich in lead compounds, has a great affinity for chromate ions. The Cr(VI) removal yield decreased with increasing initial concentration of Cr(VI) solution. An increase in the dosage of ZER caused an increase in the removal yield and the concentration of Pb, Cd and Zn released from ZER into the treated solution. The effect of temperature showed the removal process is endothermic. The removal process was highly pH dependent. 100 % removal of Cr(VI) was obtained at initial pH about 5.0 and 11.0 for the initial Cr(VI) concentration of 100 mg l−1 at 25 °C and 5 mg l−1 ZER dosage for contact time of 60 min. The removal percentage of Cr(VI) declined at pHs other than those mentioned above. Minimum removal (26.5 %) was observed at initial pH value of 3.05. XRD analysis showed t...