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55 results on '"Moses, S. A."'

1. Sex differences in permanent pacemaker implantation after transcatheter aortic valve replacement: a systematic review and meta-analysis

Author

Rivera, Frederick Berro, primary, Cha, Sung Whoy, additional, Aparece, John Paul, additional, Gonzales, Jacques Simon T., additional, Salva, Wailea Faye C., additional, Bantayan, Nathan Ross B., additional, Carado, Genquen Phillip, additional, Sharma, Vikram, additional, Al-Abcha, Abdullah, additional, Co, Michael Lawrenz, additional, Collado, Fareed Moses S., additional, and Volgman, Annabelle Santos, additional

Published
2023
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2. Chemical Composition, Antibacterial and Antifungal Activities of the Leaf Essential Oil of Afraegle paniculata (Schumach. & Thonn.) Engl

Author

Tolulope Ewekeye, Moses S. Owolabi, Akintayo L. Ogundajo, Noura S. Dosoky, William N. Setzer, and Olubunmi J. Sharaibi

Subjects
Antifungal, Traditional medicine, medicine.drug_class, Organic Chemistry, Biology, biology.organism_classification, Biochemistry, Analytical Chemistry, Afraegle paniculata, law.invention, Rutaceae, law, medicine, Chemical composition, psychological phenomena and processes, Essential oil
Abstract

Leaves of Afraegle paniculata were collected from southwestern Nigeria and hydrodistilled to give an essential oil in 0.56 % yield. The essential oil was analyzed by gas chromatography-mass spectro...

Published
2020

5. Chemical Composition of Essential Oil from the Leaves ofClerodendrum polycephalumBaker growing in Nigeria

Author

Moses S. Owolabi, Isiaka A. Ogunwande, Olamidisun A. Owoyele, and Akintayo L. Ogundajo

Subjects
010405 organic chemistry, Chemistry, Monoterpene, Organic Chemistry, Ionization detector, Mass spectrometry, Sesquiterpene, 01 natural sciences, Biochemistry, 0104 chemical sciences, Analytical Chemistry, law.invention, 010404 medicinal & biomolecular chemistry, chemistry.chemical_compound, law, Chemical constituents, Botany, Clerodendrum polycephalum, Organic chemistry, Chemical composition, Essential oil
Abstract

The essential oil obtained from the hydrodistillation of the leaf of Clerodendrum polycephalum Baker collected from Badagary, Nigeria was analyzed by gas chromatography-flame ionization detector (GC-FID) and gas chromatography-mass spectrometry (GC-MS). Forty compounds, representing 97.2 % of the total oil contents were identified in the essential oil. Sesquiterpene hydrocarbons (74.1 %) and oxygenated sesquiterpene (11.9 %) are main classes of compounds present in the oil. Monoterpene compounds totalling 10.6 % of the oil contents were also identified in the oil. The main constituents of the oil were β-caryophyllene (28.9 %), α-muurolene (9.0 %) and β-pinene (8.6 %). There were significant amounts of 1,5,9,9-tetramethyl-Z,Z,Z,Z-cycloundecatriene (7.4 %), 9-epi-(E)-caryophyllene (5.6 %) and (E)-nerolidol (5.5 %). The present study represents the first report on the chemical constituents of the volatile oil of Clerodendrum polycephalum.

Published
2016

11. Nutraceuticals for prostate cancer chemoprevention: from molecular mechanisms to clinical application

Author

Ying Huang, Andy Chang, Doreen Pon, Zhijun Wang, Steven Yeung, Jeffery Fan, Moses S. S. Chow, and Mandy Liu

Subjects
Male, Resveratrol, Pharmacology, medicine.disease_cause, Bioinformatics, Prostate cancer, chemistry.chemical_compound, Nutraceutical, Animals, Anticarcinogenic Agents, Humans, Medicine, Pharmacology (medical), business.industry, Prostatic Neoplasms, General Medicine, medicine.disease, Green tea, Clinical trial, chemistry, Expert opinion, Dietary Supplements, business, Carcinogenesis, Sulforaphane
Abstract

Nutraceutical is a food, or part of a food, used for the prevention and/or treatment of diseases. A number of nutraceuticals serve as candidates for development of prostate cancer chemopreventive agents because of promising epidemiological, preclinical and pilot clinical findings. Their mechanisms of action may involve an ability to target multiple molecular pathways in carcinogenesis without eliciting toxic side effects.This review provides an overview of several nutraceuticals, including green tea polyphenol, omega-3 fatty acids, vitamin D, lycopene, genistein, quercetin, resveratrol and sulforaphane, for the clinical relevance to chemoprevention of prostate cancer. Their mechanisms of action on regulating key processes of carcinogenesis are also discussed. For each of these agents, a brief summary of completed or currently ongoing clinical trials related to the chemopreventive efficacy on prostate cancer is given.Even though a few clinical trials have been conducted, review of these results indicate that further studies are required to confirm the clinical efficacy and safety, and to provide a guidance on how to use nutraceuticals for optimal effect. Future cancer prevention clinical trials for the nutraceuticals should recruit men with an increased risk of prostate cancer.

Published
2013

12. The Leaf Essential Oil ofMomordica charantiafrom Nigeria is Dominated by Geijerene and Pregeijerene

Author

Moses S. Owolabi, Oluwole E. Omikorede, Prajwal Paudel, Kamil A. Yusuf, and William N. Setzer

Subjects
Momordica, biology, Chemistry, Organic Chemistry, biology.organism_classification, Mass spectrometry, Biochemistry, Analytical Chemistry, law.invention, Horticulture, law, Botany, Gas chromatography, Essential oil, Germacrene D
Abstract

The leaf essential oil of Momordica charantia was obtained by hydrodistillation and analyzed by gas chromatography- mass spectrometry. The leaf oil was rich in geijerene (11.2 %), pregeijerene (27.1 %), α-pinene (14.0 %), β-pinene (7.1 %), (E)-caryophyllene (4.6 %), and germacrene D (8.6 %); remarkably different from previous reports of this plant.

Published
2013

13. Chemical Composition of the Seed Volatiles ofAframomum sceptrum(Oliv. & T. Hanb.) K. Schum. from Nigeria

Author

Moses S. Owolabi, Maria C. Palazzo, Labunmi Lajide, Adekemi Moronkola, and William N. Setzer

Subjects
biology, Chemistry, Organic Chemistry, Bacillus cereus, medicine.disease_cause, biology.organism_classification, Biochemistry, Analytical Chemistry, law.invention, law, Staphylococcus aureus, Botany, medicine, Zingiberaceae, Food science, Antibacterial activity, Escherichia coli, Chemical composition, Essential oil, Gram
Abstract

The steam distilled volatile oil obtained from pulverized Aframomum sceptrum seeds was examined by gas chromatography-mass spectrometry (GC-MS). The major components were 1,8-cineole (81.9 %), α-terpineol (10.1 %) and β-pinene (4.8 %). The oil displayed no antibacterial activity against either Gram positive organisms such as Bacillus cereus, Staphylococcus aureus, or Gram negative organisms such as Escherichia coli, (MIC = 625 μg/mL).

Published
2010

14. Cymbopogon citratus(DC) Stapf Volatile Oil from South - West, Nigeria

Author

Valery A. Isidorov, Moses S. Owolabi, Matthew O. Oladimeji, Palanisamy Marimuthu, Labunmi Lajide, and Gurdip Singh

Subjects
Organic Chemistry, Biology, medicine.disease, biology.organism_classification, Citral, Biochemistry, Analytical Chemistry, law.invention, chemistry.chemical_compound, Linalool, chemistry, law, Cymbopogon citratus, Myrcene, Botany, Serratia marcescens, medicine, Food science, Klebsiella pneumonia, Bacteria, Essential oil
Abstract

Chemical analysis of the volatile oil of Cymbopogon citratus and its antibacterial effects were investigated. Chemical analysis of the C. citratus oil was determined using Gas Chromatograph-Mass Spectrometry technique. Out of 47 peaks (representing 97.36 % of the total oil), 37 constituents were identified representing 90.86 % of the total oil constituents. The major constituents were geranial (40.9 %), neral (29.7 %), myrcene (11.3 %), linalool (1.7 %) and geranylacetate (1.6 %). The oil was examined against six bacteria; Escherichia coli, Pseudomonas aeruginosa, Salmonella typhimurium, Klebsiella pneumonia, Serratia marcescens and Staphlycoccus aureus. It was found that C. citratus inhibited the growth of all tested microorganism.

Published
2008

18. Volatile Components from the Stem Bark ofVitellaria paradoxa

Author

Moses S. Owolabi, Labunmi Lajide, Prajwal Paudel, and William N. Setzer

Subjects
Stem bark, Traditional medicine, Chemistry, Organic Chemistry, complex mixtures, Biochemistry, Analytical Chemistry, law.invention, chemistry.chemical_compound, Linalool, Germacrene, law, visual_art, Botany, visual_art.visual_art_medium, Bark, Gas chromatography, Antibacterial activity, Essential oil, Germacrene D
Abstract

The volatile oil from the stem bark of Vitellaria paradoxa (shea) has been obtained by hydrodistillation and analyzed by GC-MS. The oil is characterized by a high concentration of germacrene D (21.8 %), with smaller quantities of linalool (6.5 %), (E)-caryophyllene (6.3 %), (E)-phytol (4.9 %), and β-elemene (3.8 %). The V. paradoxa bark oil was screened for antibacterial activity but was inactive (MIC ≥ 625 μg/mL).

Published
2012

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