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2 results on '"Nathalie Grardel"'

1. Increased risk of adverse acute myeloid leukemia after anti-CD19-targeted immunotherapies in KMT2A-rearranged acute lymphoblastic leukemia: a case report and review of the literature

Author

Luca Inchiappa, Elise Fournier, Catherine Roche-Lestienne, Nicolas Duployez, Frédérique Danicourt, Florent Dumezy, Christophe Roumier, Claude Preudhomme, Loïc Fournier, Nathalie Grardel, Maxime Bemba, Carole Delattre, Agnès Daudignon, Gauthier Decool, and Jean-Michel Pignon

Subjects
Cancer Research, Methyltransferase, Myeloid, complex mixtures, 03 medical and health sciences, 0302 clinical medicine, hemic and lymphatic diseases, medicine, Epigenetics, neoplasms, biology, business.industry, Myeloid leukemia, Hematology, Gene rearrangement, medicine.disease, Haematopoiesis, Leukemia, medicine.anatomical_structure, KMT2A, Oncology, 030220 oncology & carcinogenesis, Cancer research, biology.protein, bacteria, business, 030215 immunology
Abstract

The KMT2A gene encodes a lysine-specific methyltransferase which is essential in epigenetic regulation during early development and hematopoiesis. KMT2A, also known as MLL (mixed-lineage leukemia),...

Published
2019
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2. Expression ofHMGA2in PB leukocytes and purifiedCD34+cells from controls and patients with Myelofibrosis andmyeloid metaplasia

Author

Christophe Desterke, Joris Andrieux, Brigitte Dupriez, Eric Lippert, Jean-Loup Demory, Nathalie Grardel, Olivier Pierre-Louis, Vincent Praloran, Chrystele Bilhou-Nabera, Marie-Caroline Le Bousse-Kerdilès, and Jean Luc Laï

Subjects
Cancer Research, Myeloid, biology, Chemistry, Cd34 cells, Hematology, medicine.disease, law.invention, medicine.anatomical_structure, HMGA2, Oncology, law, Metaplasia, medicine, biology.protein, Cancer research, Reactive fibrosis, Progenitor cell, medicine.symptom, Myelofibrosis, Polymerase chain reaction
Abstract

Myelofibrosis with myeloid metaplasia (MMM) is a rare myeloproliferative disorder which associates clonal proliferation of multi-potent hematologic progenitors and reactive fibrosis [1]. The karyot...

Published
2006
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