1. Synthesis of (±)-Homosarkomycin and (±)-Rosaprostol
- Author
-
Tsutomu kainuki, Mitsuru Nakayama, and Shinji Tanimori
- Subjects
Cyclopropanes ,Magnetic Resonance Spectroscopy ,Stereochemistry ,Carboxylic acid ,Cyclopentanes ,Ring (chemistry) ,Applied Microbiology and Biotechnology ,Biochemistry ,Analytical Chemistry ,Cyclopropane ,chemistry.chemical_compound ,Nucleophile ,Prostaglandins, Synthetic ,Methods ,Homosarkomycin ,Molecular Biology ,chemistry.chemical_classification ,Addition reaction ,Organic Chemistry ,Prostanoic Acids ,Stereoisomerism ,General Medicine ,Rosaprostol ,chemistry ,Indicators and Reagents ,Enone ,Biotechnology - Abstract
(±)-Homosarkomycin (2) and (±)-rosaprostol (3) were synthesized from (±)-methyl 2-oxo-bicyclo[3.1.0]hexane-1-carboxylate (1) by using the nucleophilic ring opening reaction on the double-activated cyclopropane ring as the key step.
- Published
- 1992