1. Circumcision is a primary preventive against HIV infection: Critique of a contrary meta-regression analysis by Van Howe
- Author
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Brian J. Morris, Richard G. Wamai, John N. Krieger, and Gia Elise Barboza
- Subjects
Male ,Population ,Human immunodeficiency virus (HIV) ,HIV Infections ,medicine.disease_cause ,03 medical and health sciences ,0302 clinical medicine ,medicine ,Humans ,Meta-regression ,030212 general & internal medicine ,education ,education.field_of_study ,030505 public health ,business.industry ,Confounding ,Public Health, Environmental and Occupational Health ,HIV ,Odds ratio ,Circumcision, Male ,Male circumcision ,Meta-analysis ,Africa ,Regression Analysis ,0305 other medical science ,business ,Developed country ,Demography - Abstract
A meta-analysis by Van Howe of 109 populations confirms the well-known association of male circumcision (MC) with reduced HIV prevalence. He then performed meta-regression adjusting for location, risk and MC prevalence. When one or two of these adjustments in combination were applied MC appeared protective, but when all three were introduced the association remained significant in high-risk populations, but not in general populations within Africa with a hypothetical MC prevalence of
- Published
- 2016
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