1. Emodinol, ß-Glucuronidase Inhibiting Triterpene fromPaeonia Emodi
- Author
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Naheed Riaz, Shahida Shujaat, Abdul Malik, Zaheer Ahmed, Itrat Anis, Pir Muhammad, Aziz-ur-Rehman, and Atta-ur-Rahman
- Subjects
chemistry.chemical_classification ,Magnetic Resonance Spectroscopy ,Chloroform ,Molecular Structure ,biology ,Stereochemistry ,Organic Chemistry ,Plant Science ,Paeonia ,biology.organism_classification ,Biochemistry ,Triterpenes ,Paeonia emodi ,Analytical Chemistry ,chemistry.chemical_compound ,chemistry ,Triterpene ,Oleanolic Acid ,S glucuronidase ,Two-dimensional nuclear magnetic resonance spectroscopy ,Glucuronidase ,Benzoic acid - Abstract
Emodinol, a new oleane type triterpene, has been isolated from the chloroform soluble fraction of Paeonia emodi. The structure 1beta, 3beta, 23-trihydroxyolean-12-en-28-oic acid 1 has been assigned on the basis of spectral studies including 2D NMR. It showed significant beta-glucuronidase inhibitory activity. In addition benzoic acid and 3-hydroxybenzoic acid have also been reported for the first time from this species.
- Published
- 2003
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