1. Determining pesticide residues in wheat flour by ultrahigh-performance liquid chromatography/quadrupole time-of-flight mass spectrometry with QuEChERS extraction
- Author
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Nho-Eul Song, Yun-Yeol Lee, Tae-Gyu Lim, Tae-gyu Nam, Miyoung Yoo, and Dan-Bi Kim
- Subjects
Time Factors ,Health, Toxicology and Mutagenesis ,Flour ,Wheat flour ,Food Contamination ,Toxicology ,Quechers ,Mass spectrometry ,01 natural sciences ,Mass Spectrometry ,Quadrupole time of flight ,Chromatography, High Pressure Liquid ,Triticum ,Chromatography ,Pesticide residue ,010405 organic chemistry ,Chemistry ,Crop yield ,Solid Phase Extraction ,fungi ,010401 analytical chemistry ,Extraction (chemistry) ,Pesticide Residues ,Public Health, Environmental and Occupational Health ,food and beverages ,General Chemistry ,General Medicine ,Pesticide ,0104 chemical sciences ,Food Analysis ,Food Science - Abstract
Pesticides are used to increase crop yields and preserve quality by protecting crops against pests; however, their overuse can adversely affect human health and the environment. Herein, we report the development of a multi-pesticide screening method using optimized QuEChERS coupled with liquid chromatography/quadrupole time-of-flight (QTOF) mass spectrometry for the analysis of 13 pesticides in wheat flour. Mass accuracies with errors of less than 2.4 ppm were obtained for all analysed pesticides, and the method provided satisfactory recovery and linearity. Repeatabilities of 0.3-12.7% and reproducibilities of 2.5-15.2% were observed in full-scan TOF mode. The performance of the developed full-scan TOF method was compared to that obtained in high-resolution multiple reaction monitoring (MRM-HR) mode. The limits of quantification for the full-scan TOF and MRM-HR modes ranged from 2 to 10, and 3 to 9 μg kg
- Published
- 2019