1. A New Noninvasive System for Clinical Pulse Wave Velocity Assessment: The Athos Device
- Author
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Alessandro Sanginario, Davide Lena, Alberto Milan, Dario Leone, Danilo Demarchi, Irene Buraioli, and Giulia Mingrone
- Subjects
Correctness ,business.product_category ,Computer science ,Interface (computing) ,pulse wave velocity ,Biomedical Engineering ,02 engineering and technology ,Pulse Wave Analysis ,Arterial pulse ,arterial stiffness ,intersecting tangent algorithm ,pulse transit time ,tonometry ,Software ,0202 electrical engineering, electronic engineering, information engineering ,Humans ,Electrical and Electronic Engineering ,MATLAB ,Pulse wave velocity ,Simulation ,computer.programming_language ,Graphical user interface ,business.industry ,020208 electrical & electronic engineering ,Process (computing) ,Reproducibility of Results ,Femoral Artery ,Laptop ,business ,computer ,Algorithms - Abstract
This paper presents a low cost, noninvasive, clinical-grade Pulse Wave Velocity evaluation device. The proposed system relies on a simultaneous acquisition of femoral and carotid pulse waves to improve estimation accuracy and correctness. The sensors used are two high precision MEMS force sensors, encapsulated in two ergonomic probes, and connected to the main unit. Data are then wirelessly transmitted to a standard laptop, where a dedicated graphical user interface (GUI) runs for analysis and recording. Besides the interface, the Athos system provides a Matlab algorithm to process the signals quickly and achieve a reliable PWV assessment. To better compare the results at the end of each analysis, a detailed report is generated, including all the relevant examination information (subject data, mean PTT, and obtained PWV). A pre-clinical study was conducted to validate the system by realizing several Pulse Wave Velocity measurements on ten heterogeneous healthy subjects of different ages. The collected results were then compared with those measured by a well-established and largely more expensive clinical device (SphygmoCor).
- Published
- 2021