1. Using of Procalcitonin Level in Differentiation between Bacterial Vaginitis Due to Pathogenic Bacteria and Normal Flora.
- Author
-
Salih, Eman Ghadhban, Dawood, Mohammed Ismael, and Tektook, Nihad Khalawe
- Subjects
BACTERIAL vaginitis ,PATHOGENIC bacteria ,CALCITONIN ,PREGNANT women ,VENOUS puncture ,MISOPROSTOL ,KLEBSIELLA pneumoniae ,KLEBSIELLA - Abstract
This study conducted to view the role of PCT level in initial finding of bacterial vaginitis in pregnant women. A total of 150 deep vaginal swabs (100 pregnant women and 50 pregnant women as control group) were collected from the beginning of February 2019 to the end of May 2019 from inpatients and outpatients women attended to Al-Fallujah teaching hospital. Media were organized & purified according to producer’s guidance. The ready media were utilized for segregation, definition of the viable enumeration, identifying & sensibility workout these media were achieved in the wake of being solidified. Swabs was inoculated bacteriological agars for isolation of causative bacterial types . Blood samples collected by vein puncture for determination of PCT by using ELISA technique. The study showed that that 57% of pregnant women have vaginal swab for culture as compared with 48 of the control group (non- pregnant women). The results demonstrated that, 54.39% of pathogenic bacteria isolated from vagina of pregnant women was G-ve bacteria and 45.61% was G+ve bacteria. S. aureus represented the highest rate of pathogenic isolates 45.61% in cases (43.86%) while 29.17 of the control group were infected equally by E coli and K. pneumonia.The highest rate of antibiotic sensitivity toward S. aureus isolates was occurred in levofloxacin (88.46%) while it was completely resistant to ampicillin and lincomycin, 94.11% of E. coli isolates was sensitive to each of levofloxacin and cefotaxime and 100% resistant to lincomycin, 92.85% of Klebsiella isolates was sensitive to amoxicalve while it was 100% resistant to ampicillin, erythromycin and lincomycin. Procalcitonin level was highly elevated among pregnant ones followed by healthy ones (26.79±9.4 v.s 9.236±0.6 pg/ml) at P value <0.01. The highest mean of Procalcitoninlevel is found among pregnant women with pathogenic bacteria isolates of HVS culture (30.15±9.84 pg/ml) and the lowest mean is recorded among pregnant women with normal flora isolates (23.72±7.25 pg/ml).Conclusions: Serum PCT was highly elevated in pregnant women with vaginitis especially who diagnosed with pathogenic bacteria. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF