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Your search keyword '"Sipala, Valeria"' showing total 5 results
Start Over Author "Sipala, Valeria" Publisher institute of physics publishing ltd.
5 results on '"Sipala, Valeria"'

1. Proton Computed Tomography: Iterative image reconstruction and dose evaluation

Author

Civinini, C, Bonanno, D, Brianzi, M, Carpinelli, M, Cirrone, G, Cuttone, G, Presti, D, Maccioni, G, Pallotta, S, Randazzo, N, Scaringella, M, Romano, F, Sipala, V, Talamonti, C, Vanzi, E, Bruzzi, M, Bonanno, D., Brianzi, M., CARPINELLI, Massimo, Cirrone, G. A. P., Cuttone, G., Presti, D. Lo, Maccioni, G., Pallotta, S., Randazzo, N., Scaringella, M., Romano, F., SIPALA, Valeria, Talamonti, C., Vanzi, E., Bruzzi, M., Civinini, C, Bonanno, D, Brianzi, M, Carpinelli, M, Cirrone, G, Cuttone, G, Presti, D, Maccioni, G, Pallotta, S, Randazzo, N, Scaringella, M, Romano, F, Sipala, V, Talamonti, C, Vanzi, E, Bruzzi, M, Bonanno, D., Brianzi, M., CARPINELLI, Massimo, Cirrone, G. A. P., Cuttone, G., Presti, D. Lo, Maccioni, G., Pallotta, S., Randazzo, N., Scaringella, M., Romano, F., SIPALA, Valeria, Talamonti, C., Vanzi, E., and Bruzzi, M.

Abstract

Proton Computed Tomography (pCT) is a medical imaging method with a potential for increasing accuracy of treatment planning and patient positioning in hadron therapy. A pCT system based on a Silicon microstrip tracker and a YAG:Ce crystal calorimeter has been developed within the INFN Prima-RDH collaboration. The prototype has been tested with a 175 MeV proton beam at The Svedberg Laboratory (Uppsala, Sweden) with the aim to reconstruct and characterize a tomographic image. Algebraic iterative reconstruction methods (ART), together with the most likely path formalism, have been used to obtain tomographies of an inhomogeneous phantom to eventually extract density and spatial resolutions. These results will be presented and discussed together with an estimation of the average dose delivered to the phantom and the dependence of the image quality on the dose. Due to the heavy computation load required by the algebraic algorithms the reconstruction programs have been implemented to fully exploit the high calculation parallelism of Graphics Processing Units. An extended field of view pCT system is in an advanced construction stage. This apparatus will be able to reconstruct objects of the size of a human head making possible to characterize this pCT approach in a pre-clinical environment.

Published
2017

2. Design and characterisation of a YAG(Ce) calorimeter for proton Computed Tomography application

Author

Sipala, V, Randazzo, N, Aiello, S, Bruzzi, M, Bucciolini, M, Carpinelli, M, Cirrone, G, Civinini, C, Cuttone, G, Leonora, E, Lo Presti, D, Pallotta, S, Pugliatti, C, Scaringella, M, Stancampiano, C, Talamonti, C, Vanzi, E, SIPALA, Valeria, Randazzo, N., Aiello, S., Bruzzi, M., Bucciolini, M., CARPINELLI, Massimo, Cirrone, G. A. P., Civinini, C., Cuttone, G., Leonora, E., Lo Presti, D., Pallotta, S., Pugliatti, C., Scaringella, M., Stancampiano, C., Talamonti, C., Vanzi, E., Sipala, V, Randazzo, N, Aiello, S, Bruzzi, M, Bucciolini, M, Carpinelli, M, Cirrone, G, Civinini, C, Cuttone, G, Leonora, E, Lo Presti, D, Pallotta, S, Pugliatti, C, Scaringella, M, Stancampiano, C, Talamonti, C, Vanzi, E, SIPALA, Valeria, Randazzo, N., Aiello, S., Bruzzi, M., Bucciolini, M., CARPINELLI, Massimo, Cirrone, G. A. P., Civinini, C., Cuttone, G., Leonora, E., Lo Presti, D., Pallotta, S., Pugliatti, C., Scaringella, M., Stancampiano, C., Talamonti, C., and Vanzi, E.

Abstract

The design and the characterization of a calorimeter system, aimed at measuring the residual energy in a proton Computed Tomography (pCT) apparatus, is described. The calorimeter has a 6×6cm2 active area to fully cover the tracker area of the pCT system, being 10 cm thick it is able to stop up to 200 MeV protons and sustain 1MHz particle rate (average rate on the whole area). The YAG(Ce) scintillator is promising for charged particle detection applications where high-count rate, good energy resolution and compact photodiode readout, not influenced by magnetic fields, are of importance. The aim of this work is to show data acquired with proton beam energy up to 175 MeV and to discuss the performances of this calorimeter.

Published
2015

3. A proton Computed Tomography based medical imaging system

Author

Scaringella, M, Bruzzi, M, Bucciolini, M, Carpinelli, M, Cirrone, G, Civinini, C, Cuttone, G, Lo Presti, D, Pallotta, S, Pugliatti, C, Randazzo, N, Romano, F, Sipala, V, Stancampiano, C, Talamonti, C, Vanzi, E, Zani, M, Scaringella M., Bruzzi M., Bucciolini M., CARPINELLI, Massimo, Cirrone G. A. P., Civinini C., Cuttone G., Lo Presti D., Pallotta S., Pugliatti C., Randazzo N., Romano F., SIPALA, Valeria, Stancampiano C., Talamonti C., Vanzi E., Zani M., Scaringella, M, Bruzzi, M, Bucciolini, M, Carpinelli, M, Cirrone, G, Civinini, C, Cuttone, G, Lo Presti, D, Pallotta, S, Pugliatti, C, Randazzo, N, Romano, F, Sipala, V, Stancampiano, C, Talamonti, C, Vanzi, E, Zani, M, Scaringella M., Bruzzi M., Bucciolini M., CARPINELLI, Massimo, Cirrone G. A. P., Civinini C., Cuttone G., Lo Presti D., Pallotta S., Pugliatti C., Randazzo N., Romano F., SIPALA, Valeria, Stancampiano C., Talamonti C., Vanzi E., and Zani M.

Abstract

This paper reports on the activity of the INFN PRIMA/RDH collaboration in the development of proton Computed Tomography (pCT) systems based on single proton tracking and residual energy measurement. The systems are made of a silicon microstrip tracker and a YAG:Ce crystal calorimeter to measure single protons trajectory and residual energy, respectively. A first prototype of pCT scanner, with an active area of about 5 × 5 cm2 and a data rate capability of 10 kHz, has been constructed and characterized with 62 MeV protons at INFN Laboratori Nazionali del Sud in Catania (Italy) and with 180 MeV protons at The Svedberg Laboratory (TSL) in Uppsala (Sweden). Results of these measurements, including tomographic reconstructions of test phantoms, will be shown and discussed. An upgraded system with an extended field of view (up to ∼ 5 × 20 cm2) and an increased event rate capability up to one MHz, presently under development, will be also described.

Published
2014

4. A proton Computed Tomography system for medical applications

Author

Sipala, V, Bruzzi, M, Bucciolini, M, Carpinelli, M, Cirrone, G, Civinini, C, Cuttone, G, Lo Presti, D, Pallotta, S, Pugliatti, C, Randazzo, N, Romano, F, Scaringella, M, Stancampiano, C, Talamonti, C, Tesi, M, Vanzi, E, Zani, M, SIPALA, Valeria, Bruzzi M, Bucciolini M, CARPINELLI, Massimo, Cirrone GAP, Civinini C, Cuttone G, Lo Presti D, Pallotta S, Pugliatti C, Randazzo N, Romano F, Scaringella M, Stancampiano C, Talamonti C, Tesi M, Vanzi E, Zani M., Sipala, V, Bruzzi, M, Bucciolini, M, Carpinelli, M, Cirrone, G, Civinini, C, Cuttone, G, Lo Presti, D, Pallotta, S, Pugliatti, C, Randazzo, N, Romano, F, Scaringella, M, Stancampiano, C, Talamonti, C, Tesi, M, Vanzi, E, Zani, M, SIPALA, Valeria, Bruzzi M, Bucciolini M, CARPINELLI, Massimo, Cirrone GAP, Civinini C, Cuttone G, Lo Presti D, Pallotta S, Pugliatti C, Randazzo N, Romano F, Scaringella M, Stancampiano C, Talamonti C, Tesi M, Vanzi E, and Zani M.

Abstract

Proton Computed Tomography (pCT) can improve the accuracy of both patient positioning and dose calculation in proton therapy, enabling to accurately reconstruct the electron density distribution of irradiated tissues. A pCT prototype, equipped with a silicon tracker and a YAG:Ce calorimeter, has been manufactured by an Italian collaboration. First tests under proton beam allowed obtaining good quality tomographic images of a non-homogeneous phantom. Manufacturing of a new large area system with real-time data acquisition is under way.

Published
2013

5. FIRST experiment: Fragmentation of ions relevant for space and therapy

Author

Agodi, C, Abou Haidar, Z, Alvarez, M, Aumann, T, Balestra, F, Battistoni, G, Bocci, A, Bohlen, T, Bondi, M, Boudard, A, Brunetti, A, Carpinelli, M, Cappuzzello, F, Cavallaro, M, Carbone, D, Cirrone, G, Cortes Giraldo, M, Cuttone, G, De Napoli, M, Durante, M, Fernandez Garcia, J, Finck, C, Foti, A, Gallardo, M, Golosio, B, Iarocci, E, Iazzi, F, Ickert, G, Introzzi, R, Juliani, D, Krimmer, J, Kurz, N, Labalme, M, Lavagno, A, Leifels, Y, Le Fevre, A, Leray, S, Marchetto, F, Monaco, V, Morone, M, Nicolosi, D, Oliva, P, Paoloni, A, Patera, V, Piersanti, L, Pleskac, R, Quesada, J, Randazzo, N, Romano, F, Rossi, D, Rosso, V, Rousseau, M, Sacchi, R, Sala, P, Sarti, A, Scheidenberger, C, Schuy, C, Sciubba, A, Sfienti, C, Simon, H, Sipala, V, Spiriti, E, Stuttge, L, Tropea, S, Younis, H, Agodi C, Abou Haidar Z, Alvarez MAG, Aumann T, Balestra F, Battistoni G, Bocci A, Bohlen TT, Bondi M, Boudard A, BRUNETTI, Antonio, CARPINELLI, Massimo, Cappuzzello F, Cavallaro M, Carbone D, Cirrone GAP, Cortes Giraldo MA, Cuttone G, De Napoli M, Durante M, Fernandez Garcia JP, Finck C, Foti A, Gallardo MI, GOLOSIO, Bruno, Iarocci E, Iazzi F, Ickert G, Introzzi R, Juliani D, Krimmer J, Kurz N, Labalme M, Lavagno A, Leifels Y, Le Fevre A, Leray S, Marchetto F, Monaco V, Morone MC, Nicolosi D, OLIVA, Piernicola, Paoloni A, Patera V, Piersanti L, Pleskac R, Quesada JM, Randazzo N, Romano F, Rossi D, Rosso V, Rousseau M, Sacchi R, Sala P, Sarti A, Scheidenberger C, Schuy C, Sciubba A, Sfienti C, Simon H, SIPALA, Valeria, Spiriti E, Stuttge L, Tropea S, Younis H., Agodi, C, Abou Haidar, Z, Alvarez, M, Aumann, T, Balestra, F, Battistoni, G, Bocci, A, Bohlen, T, Bondi, M, Boudard, A, Brunetti, A, Carpinelli, M, Cappuzzello, F, Cavallaro, M, Carbone, D, Cirrone, G, Cortes Giraldo, M, Cuttone, G, De Napoli, M, Durante, M, Fernandez Garcia, J, Finck, C, Foti, A, Gallardo, M, Golosio, B, Iarocci, E, Iazzi, F, Ickert, G, Introzzi, R, Juliani, D, Krimmer, J, Kurz, N, Labalme, M, Lavagno, A, Leifels, Y, Le Fevre, A, Leray, S, Marchetto, F, Monaco, V, Morone, M, Nicolosi, D, Oliva, P, Paoloni, A, Patera, V, Piersanti, L, Pleskac, R, Quesada, J, Randazzo, N, Romano, F, Rossi, D, Rosso, V, Rousseau, M, Sacchi, R, Sala, P, Sarti, A, Scheidenberger, C, Schuy, C, Sciubba, A, Sfienti, C, Simon, H, Sipala, V, Spiriti, E, Stuttge, L, Tropea, S, Younis, H, Agodi C, Abou Haidar Z, Alvarez MAG, Aumann T, Balestra F, Battistoni G, Bocci A, Bohlen TT, Bondi M, Boudard A, BRUNETTI, Antonio, CARPINELLI, Massimo, Cappuzzello F, Cavallaro M, Carbone D, Cirrone GAP, Cortes Giraldo MA, Cuttone G, De Napoli M, Durante M, Fernandez Garcia JP, Finck C, Foti A, Gallardo MI, GOLOSIO, Bruno, Iarocci E, Iazzi F, Ickert G, Introzzi R, Juliani D, Krimmer J, Kurz N, Labalme M, Lavagno A, Leifels Y, Le Fevre A, Leray S, Marchetto F, Monaco V, Morone MC, Nicolosi D, OLIVA, Piernicola, Paoloni A, Patera V, Piersanti L, Pleskac R, Quesada JM, Randazzo N, Romano F, Rossi D, Rosso V, Rousseau M, Sacchi R, Sala P, Sarti A, Scheidenberger C, Schuy C, Sciubba A, Sfienti C, Simon H, SIPALA, Valeria, Spiriti E, Stuttge L, Tropea S, and Younis H.

Abstract

Nuclear fragmentation processes are relevant in different fields of basic research and applied physics and are of particular interest for tumor therapy and for space radiation protection applications. The FIRST (Fragmentation of Ions Relevant for Space and Therapy) experiment at SIS accelerator of GSI laboratory in Darmstadt, has been designed for the measurement of different ions fragmentation cross sections at different energies between 100 and 1000 MeV/nucleon. The experiment is performed by an international collaboration made of institutions from Germany, France, Italy and Spain. The experimental apparatus is partly based on an already existing setup made of the ALADIN magnet, the MUSIC IV TPC, the LAND2 neutron detector and the TOFWALL scintillator TOF system, integrated with newly designed detectors in the interaction Region (IR) around the carbon removable target: a scintillator Start Counter, a Beam Monitor drift chamber, a silicon Vertex Detector and a Proton Tagger for detection of light fragments emitted at large angles (KENTROS). The scientific program of the FIRST experiment started on summer 2011 with the study of the 400 MeV/nucleon 12C beam fragmentation on thin (8mm) carbon target.

Published
2013

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