1. Effect of atherogenesis on membrane lipid constituents of rabbit erythrocytes
- Author
-
Najma Begum and Megha Singh
- Subjects
blood and hemopoietic system ,Erythrocytes ,Arteriosclerosis ,Lipid composition ,Membrane lipids ,Fatty Acids, Nonesterified ,Biology ,Membrane Lipids ,chemistry.chemical_compound ,lipid ,Cell integrity ,Animals ,Support, Non-U.S. Gov't ,Phospholipids ,Triglycerides ,peripheral vascular system ,Atherogenic diet ,Animal ,Cholesterol ,Erythrocyte Membrane ,atherogenesis ,Erythrocyte membrane ,Membrane ,chemistry ,Biochemistry ,Diet, Atherogenic ,lipids (amino acids, peptides, and proteins) ,Rabbits ,Cardiology and Cardiovascular Medicine ,Homeostasis - Abstract
Lipids from erythrocyte membranes of normal and cholesterol fed animals were isolated and the various fractions were analyzed quantitatively. Erythrocyte membrane lipid composition of animals fed with an atherogenic diet for 2 months revealed marked elevations in cholesterol followed by significant alterations in phospholipids, free fatty acids and triglycerides. These findings were discussed from the point of view of the role of membrane lipids in the maintenance of cell integrity, shape, and homeostasis.
- Published
- 1981