1. Histopathological Features and Ann Arbor Stage in Periocular Lymphoma.
- Author
-
Zschoche M, Zimpfer A, Scheef BO, Jünemann AM, Guthoff RF, Junghanss C, Hildebrandt G, Emmert S, Erbersdobler A, Kundt G, and Kakkassery V
- Subjects
- Adult, Humans, Neoplasm Recurrence, Local, Neoplasm Staging, Prognosis, Retrospective Studies, Conjunctival Neoplasms, Eye Neoplasms pathology, Orbital Neoplasms diagnosis, Orbital Neoplasms epidemiology, Orbital Neoplasms therapy
- Abstract
Background: To evaluate biodata, symptoms/signs, lymphoma type, localization, stage level, treatment choice and outcome of ocular adnexal lymphoma (OAL)., Patients and Methods: A single-center retrospective analysis of 56 patients with OAL was performed from 1998 to 2018., Results: OAL involved the orbit in 44.6%, the conjunctiva in 32.1%, the lacrimal apparatus in 14.3% and the eyelid in 8.93%. Extranodal marginal zone B-cell lymphoma (EMZL) was found in 60.7%, follicular lymphoma (FL) in 21.4%, diffuse large B-cell lymphoma in 7.14%, mantle cell lymphoma in 5.36% and chronic lymphatic leukaemia in 5.36% patients. No relapse was seen in 76%. EMZL and FL had a significantly better overall survival compared to other lymphoma types (p=0.002). Patients with Ann Arbor stage IE had a significantly better prognosis than those with stages higher than IE (p=0.048)., Conclusion: Our data suggest that clinicopathological features such as Ann Arbor stage influence survival., (Copyright© 2020, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.)
- Published
- 2020
- Full Text
- View/download PDF