1. Effect of Smoking on Cognitive Functioning in Young Saudi Adults.
- Author
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Bashir S, Alghamd F, Alhussien A, Alohali M, Alatawi A, Almusned T, and Habib SS
- Subjects
- Adolescent, Adult, Apolipoproteins E blood, Attention physiology, Brain-Derived Neurotrophic Factor blood, Case-Control Studies, Cognition Disorders etiology, Humans, Male, Memory physiology, Reaction Time, Saudi Arabia, Smoking blood, Smoking psychology, Young Adult, Cognition physiology, Smoking adverse effects
- Abstract
BACKGROUND Smoking is the predominant form of tobacco consumption and is growing worldwide, particularly in the younger generation in the Middle-East. We aimed to determine the effects of tobacco smoking on cognitive functions among young Saudi adults. MATERIAL AND METHODS We recruited a group of cigarette smokers (N=22) and a group of controls (non-smokers) (N=30) from apparently healthy male volunteers aged 18-29 years. Cognitive function was assessed by using the Cambridge Neuropsychological Automated Battery (CANTAB). The cognitive functions outcome variables were the response time (attention-switching task [AST]), and the percentage of correct response (pattern recognition memory [PRM] task). Clinical, demographic, blood markers (brain-derived neurotrophic factor (BDNF) and apolipoprotein E) were assessed between groups. RESULTS The 2 groups were matched for age and educational status. In comparison to the control group, smokers showed significant cognitive impairments in AST-Latency (p=0.001), AST-Congruent (p=0.001), and AST-Incongruent condition (p=0.001). There was not significant difference in BDNF APOE serum level between the 2 groups. CONCLUSIONS These results indicate that attention and alertness were significantly impaired in smokers compared to non-smokers.
- Published
- 2017
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