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The title compound (systematic name: 16-hydroxymethyl-12-methoxyibogamine), C21H28N2O2, was prepared by reaction of ibogaine with a formaldehyde–acetic acid solution (pH = 4). The crystal structure of this new product, belonging to the iboga indole family, is stabilized by an intermolecular O—H...N hydrogen bond. The identity of the compound was confirmed by one- and two-dimensional NMR spectroscopic techniques.

The title compound (systematic name: 1,2-dimethyl-6-methoxy-1,2,3,4-tetrahydroisoquinolin-7-ol), C12H17NO2, is a major alkaloid isolated from Hammada scoparia leaves. It belongs to the isoquinoline family and it was characterized by NMR spectroscopy and X-ray crystallographic techniques. The absolute configuration could not be reliably determined. An intermolecular O—H...N hydrogen bond is present in the crystal structure.