1. Spectroscopic measurements and terahertz imaging of the cornea using a rapid scanning terahertz time domain spectrometer
- Author
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Jiancheng Lv, Chen Sihai, Jiao Guohua, Dong Yuming, Lu Yuanfu, Liu Wenquan, Xianfeng Chen, Zhou Zhisheng, Rongbin She, and Jin-Ying Li
- Subjects
Permittivity ,Materials science ,Spectrometer ,business.industry ,Terahertz radiation ,General Physics and Astronomy ,Voice coil ,02 engineering and technology ,Dielectric ,021001 nanoscience & nanotechnology ,01 natural sciences ,010309 optics ,Optics ,medicine.anatomical_structure ,Cornea ,0103 physical sciences ,medicine ,sense organs ,Time domain ,0210 nano-technology ,business ,Terahertz time-domain spectroscopy - Abstract
Spectroscopic measurements and terahertz imaging of the cornea are carried out by using a rapid scanning terahertz time domain spectroscopy (THz-TDS) system. A voice coil motor stage based optical delay line (VCM-ODL) is developed to provide a rather simple and robust structure with both the high scanning speed and the large delay length. The developed system is used for THz spectroscopic measurements and imaging of the corneal tissue with different amounts of water content, and the measurement results show the consistence with the reported results, in which the measurement time using VCM-ODL is a factor of 360 shorter than the traditional motorized optical delay line (MDL). With reducing the water content a monotonic decrease of the complex permittivity of the cornea is observed. The two-term Debye relaxation model is employed to explain our experimental results, revealing that the fast relaxation time of a dehydrated cornea is much larger than that of a hydrated cornea and its dielectric behavior can be affected by the presence of the biological macromolecules. These results demonstrate that our THz spectrometer may be a promising candidate for tissue hydration sensing and practical application of THz technology.
- Published
- 2016