Author: "Barbeau, Emmanuel J." / Publisher: ios press - Searchworks@Jio Institute Digital Library Search Results

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Start Over Author "Barbeau, Emmanuel J." Publisher ios press

Author: Pistono, Aurélie, primary, Jucla, Mélanie, additional, Barbeau, Emmanuel J., additional, Saint-Aubert, Laure, additional, Lemesle, Béatrice, additional, Calvet, Benjamin, additional, Köpke, Barbara, additional, Puel, Michèle, additional, and Pariente, Jérémie, additional
Published: 2016
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Author: Barbeau, Emmanuel J., primary, Didic, Mira, additional, Joubert, Sven, additional, Guedj, Eric, additional, Koric, Lejla, additional, Felician, Olivier, additional, Ranjeva, Jean-Philippe, additional, Cozzone, Patrick, additional, and Ceccaldi, Mathieu, additional
Published: 2012
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Author: Saint-Aubert, Laure, primary, Planton, Mélanie, additional, Hannequin, Didier, additional, Albucher, Jean-François, additional, Delisle, Marie-Bernadette, additional, Payoux, Pierre, additional, Hitzel, Anne, additional, Viallard, Gérard, additional, Péran, Patrice, additional, Campion, Dominique, additional, Laquerrière, Annie, additional, Barbeau, Emmanuel J., additional, Puel, Michéle, additional, Raposo, Nicolas, additional, Chollet, François, additional, and Pariente, Jérémie, additional
Published: 2012
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Author: Didic, Mira, primary, Barbeau, Emmanuel J., additional, Felician, Olivier, additional, Tramoni, Eve, additional, Guedj, Eric, additional, Poncet, Michel, additional, and Ceccaldi, Mathieu, additional
Published: 2011
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Author: Saint-Aubert, Laure, Planton, Mélanie, Hannequin, Didier, Albucher, Jean-François, Delisle, Marie-Bernadette, Payoux, Pierre, Hitzel, Anne, Viallard, Gérard, Péran, Patrice, Campion, Dominique, Laquerrière, Annie, Barbeau, Emmanuel J., Puel, Michéle, Raposo, Nicolas, Chollet, François, and Pariente, Jérémie
Subjects: GENETICS of Alzheimer's disease, CHROMOSOME duplication, AMYLOID, MAGNETIC resonance imaging, NEUROLOGICAL disorders
Abstract: We report the case of a 62-year-old asymptomatic carrier of AβPP gene duplication. He was investigated by MRI and the amyloid ligand 18F-AV45, and compared to Alzheimer's disease patients (n = 11) and healthy controls (n = 11). The neuropsychological examination was normal. Cortical thickness and AV45 retention were comparable to Alzheimer's disease patients. AβPP duplication was diagnosed because cerebral amyloid angiopathy and Alzheimer's disease pathology were found on the neuropathological examination of his youngest brother, who died at 42 from intracerebral hemorrhage. This is the first description of a pre-symptomatic AβPP duplication carrier over 60, despite widespread cerebral amyloid angiopathy, 'Alzheimer's like' atrophy, and amyloid deposition. [ABSTRACT FROM AUTHOR]
Published: 2012
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