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2 results on '"Alessia Di Rienzo"'

1. Treating allergic rhinitis by sublingual immunotherapy: a review

Author

Cristoforo Incorvaia, Alessia Di Rienzo, Camilla Celani, Eleni Makrì, and Franco Frati

Subjects
rinite allergica, immunoterapia sublinguale, efficacia, sicurezza, compliance, meta-analisi, Public aspects of medicine, RA1-1270
Abstract

OBJECTIVE: Allergic rhinitis (AR) is a disease with high and increasing prevalence. The management of AR includes allergen avoidance, anti-allergic drugs, and allergen specific immunotherapy (AIT), but only the latter works on the causes of allergy and, due to its mechanisms of action, modifies the natural history of the disease. Sublingual immunotherapy (SLIT) was proposed in the 1990s as an option to traditional, subcutaneous immunotherapy. MATERIAL AND METHODS: We reviewed all the available controlled trials on the efficacy and safety of SLIT. RESULTS AND CONCLUSION: Thus far, more than 60 trials, globally evaluated in 6 meta-analyses, showed that SLIT is an effective and safe treatment for AR. However, it must be noted that to expect clinical efficacy in the current practice SLIT has to be performed following the indications from controlled trials, that is, sufficiently high doses to be regularly administered for at least 3 consecutive years.

Published
2012
Full Text
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2. Treating allergic rhinitis by sublingual immunotherapy: a review

Author

Eleni Makrì, Franco Frati, Camilla Celani, Alessia Di Rienzo, and Cristoforo Incorvaia

Subjects
Adult, Allergy, medicine.medical_specialty, Rhinitis, Allergic, Perennial, rinite allergica, Administration, Sublingual, Disease, Poaceae, compliance, Double-Blind Method, Meta-Analysis as Topic, Subcutaneous immunotherapy, Animals, Humans, Medicine, Sublingual immunotherapy, Clinical efficacy, Child, meta-analisi, Clinical Trials as Topic, efficacia, business.industry, lcsh:Public aspects of medicine, Pyroglyphidae, Public Health, Environmental and Occupational Health, Rhinitis, Allergic, Seasonal, Specific immunotherapy, lcsh:RA1-1270, General Medicine, Allergens, medicine.disease, Dermatology, Slit, sicurezza, Europe, Treatment Outcome, immunoterapia sublinguale, Desensitization, Immunologic, Meta-analysis, Immunology, Costs and Cost Analysis, Pollen, business
Abstract

OBJECTIVE: Allergic rhinitis (AR) is a disease with high and increasing prevalence. The management of AR includes allergen avoidance, anti-allergic drugs, and allergen specific immunotherapy (AIT), but only the latter works on the causes of allergy and, due to its mechanisms of action, modifies the natural history of the disease. Sublingual immunotherapy (SLIT) was proposed in the 1990s as an option to traditional, subcutaneous immunotherapy. MATERIAL AND METHODS: We reviewed all the available controlled trials on the efficacy and safety of SLIT. RESULTS AND CONCLUSION: Thus far, more than 60 trials, globally evaluated in 6 meta-analyses, showed that SLIT is an effective and safe treatment for AR. However, it must be noted that to expect clinical efficacy in the current practice SLIT has to be performed following the indications from controlled trials, that is, sufficiently high doses to be regularly administered for at least 3 consecutive years.

Published
2012
Full Text
View/download PDF

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