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The paper is concerned with analysis of angiographic findings on 62 patients with arteriovenous aneurysms (AVA) of the cerebral vessels who received proton beam stereotactic therapy in the period of 1978-1986 depending on an absorbed dose value of an irradiated volume. Proton stereotactic therapy (PST) of brain AVA located deep in the functionally important regions, can be used as an independent radical therapeutic method in such cases including inoperable ones. Complete AVA elimination from the blood flow or considerable reduction of the AVA volume was achieved in 68% of the patients after delivering a dose of approximately 40 Gy, the AVA volume being approximately 30%. Significant (p less than 0.05) correlation of PST results, a dose of irradiation and a value of the AVA irradiated volume was established in the groups with positive results and in the nonresponding groups.

Altogether 10 patients with spontaneous arteriosinusal anastomoses in the cavernous sinus area have been irradiated at the N. N. Burdenko Institute of Neurosurgery, USSR AMS. since 1983 using the synchrotron of the Institute of Theoretical and Experimental Physics. A "piercing" method with a proton beam of 12 mm in diameter (in one case 10 mm) was employed. Nine patients had unilateral anastomoses with the blood supply from branches of the internal and/or external carotid arteries, and one patient had a bilateral anastomosis. Irradiation was given in 2 fractions, in 2-3 days, the maximum total dose was 50-60 Gy. Regression of ophthalmological symptoms was noted 2-3 months after irradiation. Convalescence was noted in 8 patients, a follow-up period in 2 patients was insufficient. Of 7 patients examined by angiography complete thrombosis of the anastomosis was noted in 4, considerable reduction of the blood flow was noted in 3.