1. [Various factors of nonspecific resistance in pregnant women with anemia].
- Author
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Khadzhimetov AA, Sultanov SN, and Tsybikov NN
- Subjects
- Adult, Female, Humans, Pregnancy, Severity of Illness Index, Anemia immunology, Hypergammaglobulinemia etiology, Immunoglobulin A analysis, Immunoglobulin G analysis, Immunoglobulin M analysis, Immunoglobulins analysis, Pregnancy Complications, Hematologic immunology
- Abstract
Eighty-two women whose pregnancy was complicated by anemias of varying severity and twelve healthy pregnant women were examined. Blood plasma immunoglobulins A, G, and M were measured by immunochemical methods, as were the immune complexes of various levels and some parameters of the homeostasis system. The findings evidence a noticeable elevation of the concentrations of all immunoglobulins, of low-disperse immune aggregates in severe anemia of pregnancy, as well as intensive synthesis of immunoglobulin M in the fetus, low level of large immune complexes, and stimulation of some homeostasis components that results in consumption coagulopathy and chronic DIC syndrome. Correlations between some parameters of the blood coagulation and fibrinolysis systems, on the one hand, and humoral immunity characteristics, on the other, may be traced, among these correlations being reverse correlations between IgG level, activated recalcification time, fibrinogen concentration, and activated partial thromboplastin time.
- Published
- 1991