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Start Over Descriptor "Streptomyces matensis" Publisher japan antibiotics research association
1 results on '"Streptomyces matensis"'

1. New antitumor antibiotics, OS-4742 A1, A2, B1 and B2 produced by a strain of Streptomyces

Author

Rokurou Masuma, Haruo Tanaka, Ruiko Oiwa, Katsumi Tanaka, Satoshi Omura, and Juichi Awaya

Subjects
Pharmacology, Antibiotics, Antineoplastic, Chemical Phenomena, biology, Strain (chemistry), Anthracycline, medicine.drug_class, Chemistry, Antibiotics, Streptomyces matensis, biology.organism_classification, Antimicrobial, Streptomyces, Anti-Bacterial Agents, Microbiology, Mice, Drug Discovery, medicine, Animals, Sarcoma 180, Sugar, Bacteria
Abstract

New antibiotics, OS-4742 A1, A2, B1 and B2, were isolated from the culture broth of the strain OS-4742, which was designated as Streptomyces matensis subsp. vineus. These compounds have anthracycline chromophores and sugar moieties, but do not contain nitrogen. They possess antimicrobial activities against Gram-positive bacteria and antitumor activities against S-180 solid tumor on mice.

Published
1977

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