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Your search keyword '"Takaaki Sugihara"' showing total 9 results
Start Over Author "Takaaki Sugihara" Publisher japan society of hepatology
9 results on '"Takaaki Sugihara"'

2. A case of inflammatory hepatocellular adenoma in a young man related to long-term antiepileptic therapies

Author

Takakazu Nagahara, Yukako Matsuki, Jun-ichi Okano, Yoshiki Hoshino, Kenji Ohyama, Suguru Ikeda, Masahiko Sugitani, Kenichi Miyoshi, Hajime Isomoto, Takaaki Sugihara, and Tomomitu Matono

Subjects
medicine.medical_specialty, Hepatology, business.industry, Internal medicine, Inflammatory Hepatocellular Adenoma, Medicine, business, Gastroenterology, Term (time)
Published
2021
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3. Liver stiffness is a useful marker for assessing the therapeutic effect of angioplasty in Budd-Chiari syndrome: A case report

Author

Masahiko Koda, Ran Nagahara, Jun-ichi Okano, Yasufumi Ohuchi, Takakazu Nagahara, Yukako Matsuki, Masashi Yamane, Kenichi Miyoshi, Kenji Ohyama, Shinsaku Yata, Mika Kodani, Takaaki Sugihara, Tomomitsu Matono, Toshiaki Okamoto, and Hajime Isomoto

Subjects
medicine.medical_specialty, Hepatology, Liver stiffness, business.industry, Angioplasty, medicine.medical_treatment, Internal medicine, Therapeutic effect, Budd–Chiari syndrome, medicine, Cardiology, medicine.disease, business
Published
2018
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4. The choice of treatment and efficacy for the advanced hepatocellular carcinoma with inferior vena cava tumor thrombus (IVC-TT): a retrospective study

Author

Shinsaku Yata, Takaaki Sugihara, Tomomitsu Matono, Toshiaki Okamoto, Yoshiyuki Murawaki, Yasufumi Ohuchi, Kenichi Miyoshi, Takashi Tanimura, Michimori Kono, Keiko Hosho, Hajime Isomoto, Motoki Ametani, Masahiko Koda, and Jun-ichi Okano

Subjects
03 medical and health sciences, 0302 clinical medicine, Hepatology, business.industry, 030220 oncology & carcinogenesis, Medicine, 030211 gastroenterology & hepatology, business
Published
2016
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5. The efficacy of transjugular liver biopsy (TJLB); a retrospective analysis

Author

Jun-ichi Okano, Yasufumi Ohuchi, Shinsaku Yata, Masahiko Koda, Keiko Hosho, Kenichi Miyoshi, Takaaki Sugihara, Hajime Isomoto, Tomomitsu Matono, and Toshiaki Okamoto

Subjects
03 medical and health sciences, Pathology, medicine.medical_specialty, 0302 clinical medicine, Hepatology, business.industry, Histological diagnosis, Fragmentation (computing), medicine, 030211 gastroenterology & hepatology, business, 030218 nuclear medicine & medical imaging
Published
2016
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6. A case of sepsis due to Edwardsiella tarda with alcoholic liver cirrhosis complicated by hepatocellular carcinoma and lung cancer

Author

Takakazu Nagahara, Takaaki Sugihara, Masahiko Koda, Tomomitu Matono, Shiho Tokunaga, Tomohiko Tanino, Masaru Ueki, Jun-ichi Okano, and Yoshikazu Murawaki

Subjects
medicine.medical_specialty, Cirrhosis, Hepatology, biology, business.industry, General surgery, Edwardsiella tarda, biology.organism_classification, medicine.disease, Gastroenterology, Sepsis, Internal medicine, Hepatocellular carcinoma, medicine, Lung cancer, business
Published
2011
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7. Drug-induced hepatic injury caused by an aldose reductase inhibitor, epalrestat

Author

Takakazu Nagahara, Masahiko Koda, Masaru Ueki, Yuki Fujise, Jun Kato, Yoshikazu Murawaki, Kenji Oyama, Shiho Tokunaga, Takaaki Sugihara, Jun-ichi Okano, Tomomitsu Matono, Kinya Okamoto, Naoto Maeda, and Satoshi Kuwamoto

Subjects
Drug, chemistry.chemical_compound, Hepatology, chemistry, media_common.quotation_subject, medicine, Pharmacology, Aldose reductase inhibitor, Epalrestat, medicine.drug, media_common
Abstract

症例は60歳代の女性．平成21年2月頃から口渇・多飲・全身倦怠感が出現し，約3カ月で5 kgの体重減少を認めた．同年5月に空腹時血糖291 mg/dl ，HbA1c 12.6％と異常を認め，糖尿病および末梢神経障害の診断にてインスリン治療およびエパルレスタット150 mg/日と高コレステロール血症に対してロスバスタチンが開始された．7月中旬にAST 246 IU/L，ALT 375 IU/Lと肝機能障害を認めたため被疑薬を中止したが，肝機能障害が悪化し当科入院となった．8月中旬に総ビリルビン2.1 mg/dl ，ALT 1166 IU/Lまで上昇した．肝生検では小葉内にspotty necrosisを散見し，門脈域にはリンパ球を主体に炎症細胞浸潤を認めた．DLSTにてエパルレスタットのみが陽性であった．その後肝機能障害は改善し9月中旬にはほぼ正常となった．エパルレスタットはアルドース還元酵素阻害薬であり，糖尿病性末梢神経障害治療薬として広く用いられている．本症例はエパルレスタットでDLSTが陽性であり本剤による薬物性肝障害と診断した．

Published
2011
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8. Two cases of amebic liver abscess infected by heterosexual intercourse

Author

Shiho Tokunaga, Takaaki Sugihara, Masaru Ueki, Tomomitsu Matono, Jun-ichi Okano, Takakazu Nagahara, Yuki Fujise, Takufumi Tanimoto, Masahiko Koda, Yoshikazu Murawaki, Kenji Oyama, Kinya Okamoto, Jun Kato, Kazuhiko Yoneda, and Naoto Maeda

Subjects
medicine.medical_specialty, Hepatology, business.industry, Internal medicine, medicine, business, Amebic liver abscess, Gastroenterology
Abstract

異性間性交渉を契機に感染したアメーバ性肝膿瘍の2例を経験したため報告する．症例はそれぞれ28歳と29歳の男性で，性風俗店での口肛門性交の経験を有していた．両症例とも慢性の下痢・下血を契機に発症しており，腹部超音波検査，腹部CT検査にて肝S8に膿瘍を認めた．1例は胸腔への穿破を合併していた．膿汁の塗抹検査や糞便からはアメーバ原虫は確認されなかったが，抗アメーバ抗体が陽性であり，メトロニダゾール750 mg-1500 mg/日の内服を開始したところ，速やかに解熱し回復した．海外渡航歴が無くても，20代から60代までの男女で慢性の下痢・下血が認められる場合，性行為感染症としての赤痢アメーバ感染症を念頭において，性交渉歴について詳しく問診し，積極的に内視鏡検査の実施やアメーバ抗体を検査し，特に男性には肝膿瘍の合併が多い為に腹部超音波検査を実施する事が大切である．

Published
2010
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9. A case of early syphilitic hepatitis with hepatic granulomatous inflammation

Author

Kenji Ooyama, Masahiko Koda, Jyun-Ichi Okano, Takaaki Sugihara, Tomomitsu Matono, Keiko Hosho, Shiho Tokunaga, Takakazu Nagahara, Yoshikazu Murawaki, Kinya Okamoto, Masaru Ueki, Naoto Maeda, and Yasushi Horie

Subjects
Granulomatous inflammation, Hepatitis, medicine.medical_specialty, Hepatology, business.industry, Internal medicine, Immunology, Medicine, business, medicine.disease, Gastroenterology
Abstract

症例は54歳，男性．全身倦怠感を主訴に受診し，胆道系酵素の著明な上昇を認めた．肝炎ウイルスマーカー，抗核抗体は陰性であったが，梅毒血清反応が陽性で，陰茎に硬結を認めた．腹腔鏡検査では，肝表面に白色調小結節を認め，肝組織では肉芽腫性炎症を認めた．早期梅毒性肝炎と診断し，amoxicillin（AMPC）内服を開始後，胆道系酵素は速やかに改善した．早期梅毒性肝炎の報告は比較的稀であり，組織学的に肉芽腫性炎症を認める例も少なく，若干の文献的考察を加えて報告する．

Published
2009
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