1. Thalamic Hyperperfusion in Verbal Hallucination of Parkinsonian Patients
- Author
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Kazuto Nishinaka, Masaya Oda, Hideaki Matsui, Takafumi Miyoshi, Tamotsu Kubori, Fukashi Udaka, and Narihiro Hara
- Subjects
Male ,Elementary hallucination ,medicine.medical_specialty ,Parkinson's disease ,Hallucinations ,Perfusion scanning ,Audiology ,Internal Medicine ,medicine ,Humans ,Psychiatry ,Aged ,Tomography, Emission-Computed, Single-Photon ,Auditory hallucination ,business.industry ,Parkinson Disease ,General Medicine ,Middle Aged ,medicine.disease ,Cerebrovascular Circulation ,Regional Blood Flow ,Thalamic Nuclei ,Female ,medicine.symptom ,business - Abstract
Objective We compared brain perfusion image using 3D-SSP analysis of 123I-IMP SPECT between Parkinson's disease patients with auditory verbal hallucination and those without auditory hallucination. Methods Eighty-three cases with Parkinson's disease were studied. In 6 of these patients, auditory hallucination was noted. Among them, four cases had verbal hallucination and two other cases had elementary hallucination. Auditory hallucination was not found in the other 77 cases. Results Right thalamic perfusion was significantly increased in the verbal hallucination group compared to the group that lacked auditory hallucination. Conclusion In Parkinson's disease, the right thalamic hyperactive state may be related to verbal hallucination.
- Published
- 2007