1. Severe Thrombocytopenia and Acute Cytomegalovirus Colitis during Primary Human Immunodeficiency Virus Infection
- Author
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Akihiko Suganuma, Shugo Sasaki, Shingo Nishiki, Naoki Yanagisawa, Atsushi Ajisawa, Masanori Furuhata, and Akifumi Imamura
- Subjects
Adult ,Male ,0301 basic medicine ,Ganciclovir ,medicine.medical_specialty ,Anti-HIV Agents ,antiretroviral therapy ,030106 microbiology ,Congenital cytomegalovirus infection ,Colonoscopy ,Cytomegalovirus colitis ,Case Report ,thrombocytopenia ,HIV Infections ,Platelet Transfusion ,Gastroenterology ,03 medical and health sciences ,0302 clinical medicine ,Raltegravir Potassium ,Internal medicine ,Internal Medicine ,medicine ,Humans ,Platelet ,030212 general & internal medicine ,Colitis ,medicine.diagnostic_test ,Coinfection ,business.industry ,CMV ,HIV ,virus diseases ,General Medicine ,medicine.disease ,Raltegravir ,Treatment Outcome ,Cytomegalovirus Infections ,Immunology ,business ,medicine.drug - Abstract
We herein report the case of a 25-year-old man who was referred to our hospital due to acute cytomegalovirus (CMV) colitis. The initial blood tests showed that the patient had concurrent primary human immunodeficiency virus (HIV) infection and severe thrombocytopenia. Raltegravir-based antiretroviral therapy (ART) was initiated without the use of ganciclovir or corticosteroids and resulted in a rapid clinical improvement. Platelet transfusions were only necessary for a short period, and subsequent colonoscopy revealed a completely healed ulcer. This case implies that ART alone could be effective for treating severe thrombocytopenia during primary HIV and CMV coinfection.
- Published
- 2016