1. Two Cases of Acute Respiratory Distress Syndrome with High Values of Chlamydophila pneumoniae-Specific Antibodies
- Author
-
Sachiko Kawana, Takuya Oikawa, Sodai Narumi, Ryotaro Igusa, Taizou Shibahara, Takafumi Kobayashi, Atsushi Nakamura, Kozo Ota, and Kazunori Yoshida
- Subjects
ARDS ,Chlamydophila ,biology ,medicine.drug_class ,business.industry ,Antibiotics ,General Medicine ,Quinolone ,medicine.disease_cause ,medicine.disease ,biology.organism_classification ,respiratory tract diseases ,Pneumonia ,Antigen ,Chlamydophila pneumoniae ,Immunology ,Internal Medicine ,medicine ,biology.protein ,Antibody ,business - Abstract
We herein report two cases of acute respiratory distress syndrome (ARDS) with high values of Chlamydophila pneumoniae-specific antibodies. In the first case (a 65-year-old man), high levels of anti-C. pneumoniae antibodies (IgG and IgA) were detected on admission, and the anti-C. pneumoniae IgA level rose by Day 30. The patient was successfully treated with quinolone and steroids. In the second case (an 85-year-old man), abnormally high levels of anti-C. pneumoniae IgM were detected on admission. The patient did not recover, despite receiving treatment with several antibiotics and anti-inflammatory agents. Neither of the patients displayed other pathogen-specific antigens or antibodies. Chlamydophila pneumonia is usually mild, although it can cause severe interstitial pneumonia and ARDS in reinfected patients and the elderly.
- Published
- 2013
- Full Text
- View/download PDF