1. Temporal artery ultrasound versus temporal artery biopsy for giant cell arteritis
- Author
-
Tejal Magan, Gianni Virgili, Anna L Pouncey, Ersilia Lucenteforte, Patrick Musonda, Geoffrey Yeldham, and Usman Jaffer
- Subjects
030203 arthritis & rheumatology ,Medicine General & Introductory Medical Sciences ,medicine.medical_specialty ,business.industry ,Ultrasound ,Temporal artery biopsy ,medicine.disease ,03 medical and health sciences ,Giant cell arteritis ,0302 clinical medicine ,Medicine ,Pharmacology (medical) ,Temporal artery ,030212 general & internal medicine ,Radiology ,business ,skin and connective tissue diseases - Abstract
This is a protocol for a Cochrane Review (Diagnostic test accuracy). The objectives are as follows: To determine the diagnostic accuracy of the 'halo sign' on temporal artery ultrasound in people with suspected GCA, using the ACR 1990 Classification as a reference standard. We will consider two tests: 1. triage test before temporal artery biopsy, if temporal artery biopsy is considered: a sensitivity of at least 95% with a minimum specificity of 50% will be required to rule out GCA and avoid biopsy in patients who test positive; a specificity of 95% and a sensitivity of 50% will be required to rule in GCA and refer for biopsy patients who test negative. 2. replacement of temporal artery biopsy as one of the ACR 1990 criteria: this will be achieved if ultrasound shows sensitivity and specificity similar to biopsy.
- Published
- 2018